#BioGRID Chemical Interaction ID	BioGRID Gene ID	Entrez Gene ID	Systematic Name	Official Symbol	Synonyms	Organism ID	Organism	Action	Interaction Type	Author	Pubmed ID	BioGRID Publication ID	BioGRID Chemical ID	Chemical Name	Chemical Synonyms	Chemical Brands	Chemical Source	Chemical Source ID	Molecular Formula	Chemical Type	ATC Codes	CAS Number	Curated By	Method	Method Description	Related BioGRID Gene ID	Related Entrez Gene ID	Related Systematic Name	Related Official Symbol	Related Synonyms	Related Organism ID	Related Organism	Related Type	Notes	InChIKey
1912	125185	112399	-	EGLN3	HIFP4H3|HIFPH3|PHD3	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1913	125185	112399	-	EGLN3	HIFP4H3|HIFPH3|PHD3	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1918	128686	221120	-	ALKBH3	ABH3|DEPC-1|DEPC1|PCA1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1919	128686	221120	-	ALKBH3	ABH3|DEPC-1|DEPC1|PCA1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1937	125741	121642	-	ALKBH2	ABH2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
1938	125741	121642	-	ALKBH2	ABH2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	120	Vitamin C	Ascorbic Acid|Ascorbinsure|acidum ascorbicum|L-Ascorbic Acid|L-Ascorbate|Ascorbicap|acide ascorbique|cido ascrbico|L-(+)-ascorbic acid|acidum ascorbinicum|Ascorbate	zinc plus lozenges|vitamin c 1	DRUGBANK	DB00126	C6H8O6	small molecule	-	50-81-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
2921	110411	4255	RP11-109A6.1	MGMT	-	9606	Homo sapiens	unknown	target	Niture SK (2007)	16950796	173568	145	L-Cysteine	(2R)-2-amino-3-mercaptopropanoic acid|Cys|L-Cys|L-Cystein|(R)-2-Amino-3-mercaptopropanoic acid|L-Zystein|Cysteine|L-2-Amino-3-mercaptopropionic acid|Free Cysteine|(2R)-2-amino-3-sulfanylpropanoic acid	vamin n|primene 10%|primene 10	DRUGBANK	DB00151	C3H7NO2S	small molecule	-	52-90-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XUJNEKJLAYXESH-RUOZJJLTNA-N
3337	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3338	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Wroczynski P (2006)	16583981	173765	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3339	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3340	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Russo J (2002)	11872149	173679	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3363	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Quintanilla ME (2007)	17488809	173775	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3364	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Quintanilla ME (2006)	16961761	173776	151	NADH	DPNH|Reduced nicotinamide adenine diphosphate|Nicotinamide-adenine dinucleotide, reduced|1,4-dihydronicotinamide adenine dinucleotide|Reduced nicotinamide-adenine dinucleotide|NAD reduced form|Nicotinamide adenine dinucleotide (reduced)	-	DRUGBANK	DB00157	C21H29N7O14P2	small molecule	-	58-68-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOPGDPNILDQYTO-NNYOXOHSSA-N
3553	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Gyamfi MA (2006)	16829625	173902	156	Vitamin A	Retinol|all-trans-retinol|(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol|Vitamin A1|all-trans-retinyl alcohol|all-trans-vitamin A alcohol	infant's multiple vitamin drop	DRUGBANK	DB00162	C20H30O	small molecule	A11CA01|R01AX02|S01XA02|D10AD02	68-26-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
3554	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Huq MD (2006)	16763553	173903	156	Vitamin A	Retinol|all-trans-retinol|(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol|Vitamin A1|all-trans-retinyl alcohol|all-trans-vitamin A alcohol	infant's multiple vitamin drop	DRUGBANK	DB00162	C20H30O	small molecule	A11CA01|R01AX02|S01XA02|D10AD02	68-26-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
3555	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Maden M (2007)	17486539	173900	156	Vitamin A	Retinol|all-trans-retinol|(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol|Vitamin A1|all-trans-retinyl alcohol|all-trans-vitamin A alcohol	infant's multiple vitamin drop	DRUGBANK	DB00162	C20H30O	small molecule	A11CA01|R01AX02|S01XA02|D10AD02	68-26-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
3556	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Chambers D (2007)	17329364	173904	156	Vitamin A	Retinol|all-trans-retinol|(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol|Vitamin A1|all-trans-retinyl alcohol|all-trans-vitamin A alcohol	infant's multiple vitamin drop	DRUGBANK	DB00162	C20H30O	small molecule	A11CA01|R01AX02|S01XA02|D10AD02	68-26-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
3557	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Asson-Batres MA (2006)	16538685	173884	156	Vitamin A	Retinol|all-trans-retinol|(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol|Vitamin A1|all-trans-retinyl alcohol|all-trans-vitamin A alcohol	infant's multiple vitamin drop	DRUGBANK	DB00162	C20H30O	small molecule	A11CA01|R01AX02|S01XA02|D10AD02	68-26-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPIPGXGPPPQFEQ-OVSJKPMPSA-N
3686	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3687	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
3688	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	164	Adenosine triphosphate	Adenosine 5'-triphosphate|Adenosine-5'-triphosphate|ATP	-	DRUGBANK	DB00171	C10H16N5O13P3	small molecule	-	56-65-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKHQWZAMYRWXGA-YPLCUDRINA-N
4258	111577	5591	-	PRKDC	DNA-PKcs|DNAPK|DNPK1|HYRC|HYRC1|IMD26|XRCC7|p350	9606	Homo sapiens	unknown	target	Foukas LC (2002)	12145276	174346	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4261	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Blasina A (1999)	10531013	174349	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4262	106962	472	-	ATM	AT1|ATA|ATC|ATD|ATDC|ATE|TEL1|TELO1	9606	Homo sapiens	unknown	target	Sarkaria JN (1999)	10485486	174348	194	Caffeine	Cafine|1,3,7-trimethylpurine-2,6-dione|Theine|7-methyltheophylline|Coffein|Methyltheobromine|Koffein|Guaranine|1-methyltheobromine|Thein|tena|1,3,7-trimethyl-2,6-dioxopurine|Coffeinum|Anhydrous caffeine|Matena|1,3,7-trimethylxanthine|Caffeinum|Cafena|3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion	stay awake maximum strength|fi	DRUGBANK	DB00201	C8H10N4O2	small molecule	N06BC01|V04CG30	58-08-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RYYVLZVUVIJVGH-UHFFFAOYSA-N
4668	119071	50484	-	RRM2B	MTDPS8A|MTDPS8B|P53R2	9606	Homo sapiens	inhibitor	target	Kantarjian HM (2007)	17852710	174594	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
4669	119071	50484	-	RRM2B	MTDPS8A|MTDPS8B|P53R2	9606	Homo sapiens	inhibitor	target	Sampat K (2009)	19715446	174595	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
4670	119071	50484	-	RRM2B	MTDPS8A|MTDPS8B|P53R2	9606	Homo sapiens	inhibitor	target	Kline JP (2005)	16316309	174590	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
4671	119071	50484	-	RRM2B	MTDPS8A|MTDPS8B|P53R2	9606	Homo sapiens	inhibitor	target	Zhenchuk A (2009)	19576186	174592	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
4672	119071	50484	-	RRM2B	MTDPS8A|MTDPS8B|P53R2	9606	Homo sapiens	inhibitor	target	Takahashi T (1999)	9923554	174593	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
4673	111422	5426	-	POLE	CRCS12|FILS|POLE1	9606	Homo sapiens	inhibitor	target	Zhenchuk A (2009)	19576186	174592	235	Cladribine	2-Chlorodeoxyadenosine|(2R,3S,5R)-5-(6-amino-2-Chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol|CldAdo|2-Chloro-2'-deoxy-beta-adenosine|Cladribinum|2-chloro-Deoxyadenosine|2ClAdo|2-CdA|2-chloro-6-amino-9-(2-Deoxy-beta-D-erythro-pentofuranosyl)purine|Cladribina|2-Chloro-2'-deoxyadenosine|Cladribine	leustatin 1mg/ml|cladribine in	DRUGBANK	DB00242	C10H12ClN5O3	small molecule	L01BB04	4291-63-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PTOAARAWEBMLNO-KVQBGUIXSA-N
5197	110166	3978	-	LIG1	-	9606	Homo sapiens	inhibitor	target	Rose JL (2007)	17202402	174995	283	Bleomycin	Bleomicina|Bleomycinum|Bleomycin A2|BLM|Bleomycine|Bleomicin|Bleocin	bleomycin for injection usp|bl	DRUGBANK	DB00290	C55H84N17O21S3	small molecule	L01DC01	11056-06-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYVAGSVQBOHSSS-WXFSZRTFSA-O
5198	110168	3980	-	LIG3	LIG2	9606	Homo sapiens	inhibitor	target	Rose JL (2007)	17202402	174995	283	Bleomycin	Bleomicina|Bleomycinum|Bleomycin A2|BLM|Bleomycine|Bleomicin|Bleocin	bleomycin for injection usp|bl	DRUGBANK	DB00290	C55H84N17O21S3	small molecule	L01DC01	11056-06-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYVAGSVQBOHSSS-WXFSZRTFSA-O
7793	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	526	Guanidine	Gu|Iminourea|Aminomethanamidine|Imidourea|Guanidin|H2N-C(=NH)-NH2|GUANIDINE	guanidine hydrochloride	DRUGBANK	DB00536	CH5N3	small molecule	-	113-00-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRALSGWEFCBTJO-UHFFFAOYSA-N
7794	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	526	Guanidine	Gu|Iminourea|Aminomethanamidine|Imidourea|Guanidin|H2N-C(=NH)-NH2|GUANIDINE	guanidine hydrochloride	DRUGBANK	DB00536	CH5N3	small molecule	-	113-00-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZRALSGWEFCBTJO-UHFFFAOYSA-N
8659	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Dewar AL (2005)	15917650	177323	609	Imatinib	Imatinibum|alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide|4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide|Imatinib Methansulfonate|STI 571|Imatinib	imatinib mesylate|pms-imatinib	DRUGBANK	DB00619	C29H31N7O	small molecule	L01XE01	152459-95-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KTUFNOKKBVMGRW-UHFFFAOYSA-N
8660	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Haberler C (2006)	16205964	177326	609	Imatinib	Imatinibum|alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide|4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide|Imatinib Methansulfonate|STI 571|Imatinib	imatinib mesylate|pms-imatinib	DRUGBANK	DB00619	C29H31N7O	small molecule	L01XE01	152459-95-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KTUFNOKKBVMGRW-UHFFFAOYSA-N
8661	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Agirre X (2005)	15949566	177327	609	Imatinib	Imatinibum|alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide|4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide|Imatinib Methansulfonate|STI 571|Imatinib	imatinib mesylate|pms-imatinib	DRUGBANK	DB00619	C29H31N7O	small molecule	L01XE01	152459-95-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KTUFNOKKBVMGRW-UHFFFAOYSA-N
8662	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Brueggemeier SB (2005)	16153117	177324	609	Imatinib	Imatinibum|alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide|4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide|Imatinib Methansulfonate|STI 571|Imatinib	imatinib mesylate|pms-imatinib	DRUGBANK	DB00619	C29H31N7O	small molecule	L01XE01	152459-95-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KTUFNOKKBVMGRW-UHFFFAOYSA-N
8663	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Hoerth E (2004)	15799618	177325	609	Imatinib	Imatinibum|alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-P-toluidide|4-(4-METHYL-piperazin-1-ylmethyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide|Imatinib Methansulfonate|STI 571|Imatinib	imatinib mesylate|pms-imatinib	DRUGBANK	DB00619	C29H31N7O	small molecule	L01XE01	152459-95-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KTUFNOKKBVMGRW-UHFFFAOYSA-N
10136	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Mic FA (2004)	15366004	178209	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10137	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Gidlof AC (2006)	16837774	173874	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10138	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Matt N (2005)	16207763	119194	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10139	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Kim H (2005)	16166285	178211	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10140	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Everts HB (2004)	15245423	178212	745	Tretinoin	ATRA|Tretinoin|Tretinoine (french) (einecs)|Retin-a|all-trans-beta-Retinoic acid|All Trans-Retinoic Acid|Trtinone|All Trans Retinoic Acid|Solage|3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ecl)|Retionic Acid|trans-Retinoic acid|all-trans-Retinoic acid|RETINOIC acid|Retisol-a|Vesanoid|Ro 1-5488|Vitinoin|Renova|AGN 100335|Vitamin A acid|(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid|all-trans-Tretinoin|Tretin m|beta-Retinoic acid|all-(e)-Retinoic acid|Stieva-a|Tretinoina|Tretinoinum|all-trans-Vitamin a1 acid|Eudyna|all-trans-Vitamin a acid|Acide retinoique (french) (dsl)	tretinoin gel microsphere|viti	DRUGBANK	DB00755	C20H28O2	small molecule	L01XX14|D10AD01|D10AD51	302-79-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHGAZHPCJJPHSC-YCNIQYBTSA-N
10834	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	inhibitor	target	Mackenzie IS (2005)	16051882	178554	812	Disulfiram	Tetraethylthiuram Disulfide|Tetraethylthioperoxydicarbonic Diamide|Tetraethylthiuram Disulphide|1,1'-dithiobis(N,N-diethylthioformamide)|N,N,N',N'-tetraethylthiuram disulfide|Antabuse (tn)|Disulfiram|Bis(diethylthiocarbamoyl) disulfide	antabuse tab 0.25gm|antabuse t	DRUGBANK	DB00822	C10H20N2S4	small molecule	P03AA54|P03AA04|N07BB01	97-77-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUZONCFQVSMFAP-UHFFFAOYSA-N
10835	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	inhibitor	target	Ho MP (2007)	17220694	178555	812	Disulfiram	Tetraethylthiuram Disulfide|Tetraethylthioperoxydicarbonic Diamide|Tetraethylthiuram Disulphide|1,1'-dithiobis(N,N-diethylthioformamide)|N,N,N',N'-tetraethylthiuram disulfide|Antabuse (tn)|Disulfiram|Bis(diethylthiocarbamoyl) disulfide	antabuse tab 0.25gm|antabuse t	DRUGBANK	DB00822	C10H20N2S4	small molecule	P03AA54|P03AA04|N07BB01	97-77-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AUZONCFQVSMFAP-UHFFFAOYSA-N
11171	107776	1386	-	ATF2	CRE-BP1|CREB-2|CREB2|HB16|TREB7	9606	Homo sapiens	unknown	target	Fiebich BL (2012)	21631396	178700	842	Pseudoephedrine	L-(+)-Pseudoephedrine|Isoephedrine|Psi-ephedrine|d-Pseudoephedrine|Pseudoephedrinum|d-Isoephedrine|d-psi-Ephedrine|Pseudoefedrina|(+)-(1S,2S)-Pseudoephedrine|(+)-Pseudoephedrine|d-psi-2-Methylamino-1-phenyl-1-propanol|pseudophdrine|L(+)-psi-Ephedrine|(+)-threo-Ephedrine|(+) threo-2-(methylamino)-1-phenyl-1-propanol|Pseudoephedrine D-form|-ephedrine|(+)-psi-Ephedrine|Psi-ephedrin|trans-Ephedrine	children's tylenol cold liquid	DRUGBANK	DB00852	C10H15NO	small molecule	R01BA52|R01BA02	90-82-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KWGRBVOPPLSCSI-WCBMZHEXSA-N
12503	111419	5423	-	POLB	-	9606	Homo sapiens	inhibitor	target	Krynetskaia NF (2009)	19372559	179517	977	Cytarabine	1-beta-D-Arabinofuranosylcytosine|Cytarabine|Arabinofuranosyl Cytidine|Cytosine arabinoside|4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone|Cytarabinum|Ara-C|Cytosine-1-beta-D-arabinofuranoside|Citarabina|cytosine--D-arabinofuranoside|Cytosine-beta-D-arabinofuranoside	aj-cytarabine|cytarabine injec	DRUGBANK	DB00987	C9H13N3O5	small molecule	L01BC01	147-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHDGCWIWMRVCDJ-CCXZUQQUSA-N
12504	111419	5423	-	POLB	-	9606	Homo sapiens	inhibitor	target	Angeli JP (2006)	16866189	179516	977	Cytarabine	1-beta-D-Arabinofuranosylcytosine|Cytarabine|Arabinofuranosyl Cytidine|Cytosine arabinoside|4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone|Cytarabinum|Ara-C|Cytosine-1-beta-D-arabinofuranoside|Citarabina|cytosine--D-arabinofuranoside|Cytosine-beta-D-arabinofuranoside	aj-cytarabine|cytarabine injec	DRUGBANK	DB00987	C9H13N3O5	small molecule	L01BC01	147-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHDGCWIWMRVCDJ-CCXZUQQUSA-N
12505	111419	5423	-	POLB	-	9606	Homo sapiens	inhibitor	target	Miura S (2004)	15011952	179515	977	Cytarabine	1-beta-D-Arabinofuranosylcytosine|Cytarabine|Arabinofuranosyl Cytidine|Cytosine arabinoside|4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone|Cytarabinum|Ara-C|Cytosine-1-beta-D-arabinofuranoside|Citarabina|cytosine--D-arabinofuranoside|Cytosine-beta-D-arabinofuranoside	aj-cytarabine|cytarabine injec	DRUGBANK	DB00987	C9H13N3O5	small molecule	L01BC01	147-94-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHDGCWIWMRVCDJ-CCXZUQQUSA-N
14420	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Hwang BJ (2006)	17005224	180456	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14421	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2007)	17370311	180454	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14422	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Hyun Park W (2003)	12480548	180455	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14423	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2005)	16230390	180453	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
14424	107067	595	-	CCND1	BCL1|D11S287E|PRAD1|U21B31	9606	Homo sapiens	antagonist	target	Ouyang W (2006)	16387740	180451	1157	Arsenic trioxide	Arsenicum album|Arsenious Acid|White arsenic|Arsenigen Saure|Arseni Trioxydum|Arsenious Acid Anhydride|Arsentrioxide|Arseneous anhydride|Anhydride Arsenieux|Arsenic(III) oxide|Arseneous oxide|Oxyde Arsenieux|Acide Arsenieux|Tetraarsenic hexaoxide|Arsenic Oxidearsenous Trioxide|Arsenic oxide|Arsenolite|Arsenic sesquioxide|Diarsenic trioxide|Arsenic Blanc|Arsenious Trioxide	trisenox	DRUGBANK	DB01169	As2O3	small molecule	L01XX27	1327-53-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOQADKPFYVWPSE-UHFFFAOYSA-N
15409	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	multitarget	target	Piccaluga PP (2007)	17701954	180863	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15410	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	multitarget	target	Imming P (2006)	17016423	171742	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
15411	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	multitarget	target	Chen X (2002)	11752352	171740	1242	Dasatinib	Dasatinib (anh.)|Dasatinib|N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide|BMS dasatinib|Anhydrous dasatinib|dasatinib (anhydrous)|anh. dasatinib|Dasatinibum|BDBM13216	sprycel	DRUGBANK	DB01254	C22H26ClN7O2S	small molecule	L01XE06	302962-49-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZBNZXTGUTAYRHI-UHFFFAOYSA-N
17756	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17757	116446	11315	CTA-215D11.1	PARK7	DJ-1|DJ1|HEL-S-67p	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17758	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
17759	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1702	Double Oxidized Cysteine	-	-	DRUGBANK	DB01769	C3H6NO4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	InChIKey=GEAMCHVNTOUKJC-REOHCLBHSA-N
18017	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18018	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1815	4-[5-(Trans-4-Aminocyclohexylamino)-3-Isopropylpyrazolo[1,5-a]Pyrimidin-7-Ylamino]-N,N-Dimethylbenzenesulfonamide	-	-	DRUGBANK	DB01888	C23H33N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MDIWBYRNTPTYQI-QAQDUYKDSA-N
18259	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18260	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18261	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1916	Coenzyme A	CoA|CoA-SH|CoASH|3'-phosphoadenosine-(5')diphospho(4')pantatheine|HSCoA	-	DRUGBANK	DB01992	C21H36N7O16P3S	small molecule	-	85-61-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGJOEKWQDUBAIZ-VPHNIEJBSA-N
18334	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18335	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18336	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18337	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
18390	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18391	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18392	115779	10524	-	KAT5	ESA1|HTATIP|HTATIP1|PLIP|TIP|TIP60|ZC2HC5|cPLA2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	1962	S-Acetyl-Cysteine	-	-	DRUGBANK	DB02039	C5H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XCIRMLHOFVDUDP-SCSAIBSYSA-N
18409	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18410	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18411	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	1973	Indirubin-3'-Monoxime	-	-	DRUGBANK	DB02052	C16H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HBDSHCUSXQATPO-BGBJRWHRSA-N
18510	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18511	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18512	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2011	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB02091	C9H10N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CTFDMGIBHFQWKB-UHFFFAOYSA-N
18565	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2035	Daidzin	Daidzoside|7-O-B-D-GLUCOPYRANOSIDE|Daidzein-7-glucoside|Daidzein 7-glucoside|Daidzein 7-O-glucoside|7-(beta-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one|4',7-Dihydroxyisoflavone	-	DRUGBANK	DB02115	C21H20O9	small molecule	-	552-66-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KYQZWONCHDNPDP-QNDFHXLGSA-N
18566	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2035	Daidzin	Daidzoside|7-O-B-D-GLUCOPYRANOSIDE|Daidzein-7-glucoside|Daidzein 7-glucoside|Daidzein 7-O-glucoside|7-(beta-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one|4',7-Dihydroxyisoflavone	-	DRUGBANK	DB02115	C21H20O9	small molecule	-	552-66-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KYQZWONCHDNPDP-QNDFHXLGSA-N
18567	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2035	Daidzin	Daidzoside|7-O-B-D-GLUCOPYRANOSIDE|Daidzein-7-glucoside|Daidzein 7-glucoside|Daidzein 7-O-glucoside|7-(beta-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one|7-(beta-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-chromen-4-one|4',7-Dihydroxyisoflavone	-	DRUGBANK	DB02115	C21H20O9	small molecule	-	552-66-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KYQZWONCHDNPDP-QNDFHXLGSA-N
18569	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18573	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	2036	Olomoucine	-	-	DRUGBANK	DB02116	C15H18N6O	small molecule	-	101622-51-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GTVPOLSIJWJJNY-UHFFFAOYSA-N
18713	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18714	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18715	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2113	4-[(4-Imidazo[1,2-a]Pyridin-3-Ylpyrimidin-2-Yl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB02197	C17H14N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NKORVPQBJCGYEC-UHFFFAOYSA-N
18745	110411	4255	RP11-109A6.1	MGMT	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2128	S-Methylcysteine	-	-	DRUGBANK	DB02216	C4H9NO2S	small molecule	-	1187-84-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IDIDJDIHTAOVLG-VKHMYHEASA-N
18746	110411	4255	RP11-109A6.1	MGMT	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2128	S-Methylcysteine	-	-	DRUGBANK	DB02216	C4H9NO2S	small molecule	-	1187-84-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IDIDJDIHTAOVLG-VKHMYHEASA-N
18889	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
18890	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2204	2-Amino-6-Chloropyrazine	-	-	DRUGBANK	DB02297	C4H4ClN3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTPXVCKCLBROOJ-UHFFFAOYSA-N
19154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2310	6-O-Cyclohexylmethyl Guanine	-	-	DRUGBANK	DB02407	C12H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MWGXGTJJAOZBNW-UHFFFAOYSA-N
19290	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19291	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2380	Phosphonothreonine	-	-	DRUGBANK	DB02482	C4H10NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	USRGIUJOYOXOQJ-STHAYSLISA-N
19343	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2395	Carba-Nicotinamide-Adenine-Dinucleotide	-	-	DRUGBANK	DB02498	C22H29N7O13P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGPLSUKWXXSBCU-QQWIQQAJSA-N
19344	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2395	Carba-Nicotinamide-Adenine-Dinucleotide	-	-	DRUGBANK	DB02498	C22H29N7O13P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGPLSUKWXXSBCU-QQWIQQAJSA-N
19345	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2395	Carba-Nicotinamide-Adenine-Dinucleotide	-	-	DRUGBANK	DB02498	C22H29N7O13P2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGPLSUKWXXSBCU-QQWIQQAJSA-N
19418	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19419	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19420	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2435	N-[4-(2-Methylimidazo[1,2-a]Pyridin-3-Yl)-2-Pyrimidinyl]Acetamide	-	-	DRUGBANK	DB02538	C14H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZCRPPLDDHBLUES-UHFFFAOYSA-N
19428	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19429	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19430	113162	7314	-	UBB	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2439	(4s)-5-Fluoro-L-Leucine	-	-	DRUGBANK	DB02542	C6H12FNO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FHOARJRQRXAPOF-WHFBIAKZSA-N
19526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19527	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19528	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2497	1-Amino-6-Cyclohex-3-Enylmethyloxypurine	-	-	DRUGBANK	DB02603	C13H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPUIDVRYMVIXGO-UHFFFAOYSA-N
19620	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19621	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19622	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2538	N-(5-Cyclopropyl-1h-Pyrazol-3-Yl)Benzamide	-	-	DRUGBANK	DB02647	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LUCORKWTQSQFFU-UHFFFAOYSA-N
19706	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2579	NU1025	-	-	DRUGBANK	DB02690	C9H8N2O2	small molecule	-	90417-38-2	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJDAOHJWLUNFLX-UHFFFAOYSA-N
19729	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	2590	Nicotinamide	Nicotinic amide|Niacinamide	neogen dermalogy real fresh fo	DRUGBANK	DB02701	C6H6N2O	small molecule	A11HA01	98-92-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DFPAKSUCGFBDDF-UHFFFAOYSA-N
19815	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19816	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19817	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2621	Purvalanol	-	-	DRUGBANK	DB02733	C20H25ClN6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZKDXRFMOHZVXSG-HNNXBMFYSA-N
19986	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19987	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
19988	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2715	[4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine	-	-	DRUGBANK	DB02833	C14H12N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DYTKVFHLKPDNRW-UHFFFAOYSA-N
20095	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20096	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2778	5-{[(2-Amino-9h-Purin-6-Yl)Oxy]Methyl}-2-Pyrrolidinone	-	-	DRUGBANK	DB02898	C10H11N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZSKHIYHEECHGIB-RXMQYKEDSA-N
20127	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20128	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20129	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2794	4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(4-Trifluoromethyl-Phenyl)-Amine	-	-	DRUGBANK	DB02915	C16H13F3N4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEZFDQUDLQCVNX-UHFFFAOYSA-N
20185	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20189	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	2827	Hymenialdisine	-	-	DRUGBANK	DB02950	C11H10BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QPCBNXNDVYOBIP-WHFBIAKZSA-N
20200	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20201	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20202	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2840	(5-Chloropyrazolo[1,5-a]Pyrimidin-7-Yl)-(4-Methanesulfonylphenyl)Amine	-	-	DRUGBANK	DB02963	C13H11ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVNXHNRYPADEAD-UHFFFAOYSA-N
20215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20216	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20217	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2850	4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide	-	-	DRUGBANK	DB02973	C14H9BrN4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BWTHJLODYBOEIY-VHEBQXMUSA-N
20323	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20324	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2893	4-(2,5-Dichloro-Thiophen-3-Yl)-Pyrimidin-2-Ylamine	-	-	DRUGBANK	DB03019	C8H5Cl2N3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PAPYICJQRHSQGK-UHFFFAOYSA-N
20423	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2943	2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone	-	-	DRUGBANK	DB03072	C23H24FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LOFDUAJQRUYHBR-UHFFFAOYSA-N
20424	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2943	2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone	-	-	DRUGBANK	DB03072	C23H24FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LOFDUAJQRUYHBR-UHFFFAOYSA-N
20425	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2943	2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone	-	-	DRUGBANK	DB03072	C23H24FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LOFDUAJQRUYHBR-UHFFFAOYSA-N
20426	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	2944	3-Methoxybenzamide	-	-	DRUGBANK	DB03073	C8H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKPLPDIMEREJJF-UHFFFAOYSA-N
20427	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	2944	3-Methoxybenzamide	-	-	DRUGBANK	DB03073	C8H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKPLPDIMEREJJF-UHFFFAOYSA-N
20428	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	2944	3-Methoxybenzamide	-	-	DRUGBANK	DB03073	C8H9NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VKPLPDIMEREJJF-UHFFFAOYSA-N
20777	111419	5423	-	POLB	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3090	2'-Deoxyadenosine 5'-Triphosphate	-	-	DRUGBANK	DB03222	C10H16N5O12P3	small molecule	-	1927-31-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUYVUBYJARFZHO-DSYKOEDSSA-N
20778	111419	5423	-	POLB	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3090	2'-Deoxyadenosine 5'-Triphosphate	-	-	DRUGBANK	DB03222	C10H16N5O12P3	small molecule	-	1927-31-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUYVUBYJARFZHO-DSYKOEDSSA-N
20779	111419	5423	-	POLB	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3090	2'-Deoxyadenosine 5'-Triphosphate	-	-	DRUGBANK	DB03222	C10H16N5O12P3	small molecule	-	1927-31-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SUYVUBYJARFZHO-DSYKOEDSSA-N
20933	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20934	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
20935	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3172	4-[(6-Amino-4-Pyrimidinyl)Amino]Benzenesulfonamide	-	-	DRUGBANK	DB03307	C10H11N5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FVFVVRPJERUECT-UHFFFAOYSA-N
21040	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21041	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21042	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3227	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	-	-	DRUGBANK	DB03365	C16H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BNDYIYYKEIXHNK-UHFFFAOYSA-N
21186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Imming P (2006)	17016423	171742	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21187	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21188	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Overington JP (2006)	17139284	171741	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21189	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Berman HM (2000)	10592235	172122	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21190	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	binder	target	Chen X (2002)	11752352	171740	3285	SU9516	-	-	DRUGBANK	DB03428	C13H11N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QNUKRWAIZMBVCU-WCIBSUBMSA-N
21384	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21385	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21386	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3345	3-Pyridin-4-Yl-2,4-Dihydro-Indeno[1,2-.C.]Pyrazole	-	-	DRUGBANK	DB03490	C15H11N3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NHOACLCXCKJMAK-UHFFFAOYSA-N
21391	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21392	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21400	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21401	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Zvelebil MJ (1998)	18465538	182075	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21402	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	unknown	target	Chen X (2002)	11752352	171740	3351	Flavopiridol	Alvocidib freebase|Alvocidib	-	DRUGBANK	DB03496	C21H20ClNO5	small molecule	-	146426-40-6	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BIIVYFLTOXDAOV-YVEFUNNKSA-N
21422	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3364	2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	-	-	DRUGBANK	DB03509	C15H10ClN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FLYGLPYJEQPCFY-UHFFFAOYSA-N
21423	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3364	2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	-	-	DRUGBANK	DB03509	C15H10ClN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FLYGLPYJEQPCFY-UHFFFAOYSA-N
21424	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3364	2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide	-	-	DRUGBANK	DB03509	C15H10ClN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FLYGLPYJEQPCFY-UHFFFAOYSA-N
21535	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21536	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21537	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3431	(2e,3s)-3-Hydroxy-5'-[(4-Hydroxypiperidin-1-Yl)Sulfonyl]-3-Methyl-1,3-Dihydro-2,3'-Biindol-2'(1'h)-One	-	-	DRUGBANK	DB03583	C22H23N3O5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYOAIABDFUJDKQ-SQJPUDIVSA-N
21674	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21675	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21676	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3510	1-[(2-Amino-6,9-Dihydro-1h-Purin-6-Yl)Oxy]-3-Methyl-2-Butanol	-	-	DRUGBANK	DB03663	C10H13N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BEXUQVHWMLPYKY-UHFFFAOYSA-N
21800	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3565	3,4-Dihydro-5-Methyl-Isoquinolinone	-	-	DRUGBANK	DB03722	C10H11NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLZPXDJYADIEU-UHFFFAOYSA-N
21801	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3565	3,4-Dihydro-5-Methyl-Isoquinolinone	-	-	DRUGBANK	DB03722	C10H11NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLZPXDJYADIEU-UHFFFAOYSA-N
21802	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3565	3,4-Dihydro-5-Methyl-Isoquinolinone	-	-	DRUGBANK	DB03722	C10H11NO	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RLLZPXDJYADIEU-UHFFFAOYSA-N
21826	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21827	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21828	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3580	4-((3r,4s,5r)-4-Amino-3,5-Dihydroxy-Hex-1-Ynyl)-5-Fluoro-3-[1-(3-Methoxy-1h-Pyrrol-2-Yl)-Meth-(Z)-Ylidene]-1,3-Dihydro-Indol-2-One	-	-	DRUGBANK	DB03737	C20H20FN3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RAKYKJWUUUKCCW-MPLBGYFPSA-N
21979	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
21980	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3640	Lysine Nz-Carboxylic Acid	-	-	DRUGBANK	DB03801	C7H14N2O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PWIKLEYMFKCERQ-YFKPBYRVSA-N
22097	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3715	N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide	-	-	DRUGBANK	DB03878	C22H18N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWQVBESSYLICRX-UHFFFAOYSA-N
22286	113352	7518	-	XRCC4	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3798	S-(Dimethylarsenic)Cysteine	-	-	DRUGBANK	DB03963	C5H12AsNO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UKLXSOVDMSQHMM-SCSAIBSYSA-N
22287	113352	7518	-	XRCC4	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3798	S-(Dimethylarsenic)Cysteine	-	-	DRUGBANK	DB03963	C5H12AsNO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UKLXSOVDMSQHMM-SCSAIBSYSA-N
22373	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22374	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22375	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3840	[2-Amino-6-(2,6-Difluoro-Benzoyl)-Imidazo[1,2-a]Pyridin-3-Yl]-Phenyl-Methanone	-	-	DRUGBANK	DB04006	C21H13F2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WUGJIPFLBOATGL-UHFFFAOYSA-N
22382	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3844	2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide	-	-	DRUGBANK	DB04010	C15H13N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NVVWVYYHTKCIAE-UHFFFAOYSA-N
22390	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	inhibitor	target	Chen X (2002)	11752352	171740	3848	Alsterpaullone	-	-	DRUGBANK	DB04014	C16H11N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OLUKILHGKRVDCT-UHFFFAOYSA-N
22570	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22571	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22572	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	3933	N-[4-(2,4-Dimethyl-1,3-Thiazol-5-Yl)Pyrimidin-2-Yl]-N'-Hydroxyimidoformamide	-	-	DRUGBANK	DB04101	C10H11N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVKZTPFHUYGZBI-UHFFFAOYSA-N
22781	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22782	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
22783	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4015	N'-(Pyrrolidino[2,1-B]Isoindolin-4-On-8-Yl)-N-(Pyridin-2-Yl)Urea	-	-	DRUGBANK	DB04186	C17H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KLVYMYQTRZCMLE-CYBMUJFWSA-N
23004	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23005	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23006	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4115	2-[Trans-(4-Aminocyclohexyl)Amino]-6-(Benzyl-Amino)-9-Cyclopentylpurine	-	-	DRUGBANK	DB04288	C23H31N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTVILUUAQWQWBK-IYARVYRRSA-N
23238	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4203	Crotonaldehyde	-	-	DRUGBANK	DB04381	C4H6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLUCVPSAIODCQM-NSCUHMNNSA-N
23239	106719	217	-	ALDH2	ALDH-E2|ALDHI|ALDM	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4203	Crotonaldehyde	-	-	DRUGBANK	DB04381	C4H6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MLUCVPSAIODCQM-NSCUHMNNSA-N
23274	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23304	111825	5888	-	RAD51	BRCC5|HRAD51|HsRad51|HsT16930|MRMV2|RAD51A|RECA	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4216	Phosphoaminophosphonic Acid-Adenylate Ester	-	-	DRUGBANK	DB04395	C10H17N6O12P3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVKSNHVPLWYQGJ-FCIPNVEPSA-N
23350	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23351	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23352	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4225	4-[4-(4-Methyl-2-Methylamino-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04407	C15H15N5OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTMLAWRVLMYMDF-UHFFFAOYSA-N
23428	106718	216	RP11-151D14.2	ALDH1A1	ALDC|ALDH-E1|ALDH1|ALDH11|HEL-9|HEL-S-53e|HEL12|PUMB1|RALDH1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4261	1,4-Dithiothreitol	2,3-dihydroxy-1,4-dithiobutane	-	DRUGBANK	DB04447	C4H10O2S2	small molecule	-	3483-12-3	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VHJLVAABSRFDPM-IMJSIDKUSA-N
23499	113164	7316	-	UBC	HMG20	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4278	N-Formylmethionine	-	-	DRUGBANK	DB04464	C6H11NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PYUSHNKNPOHWEZ-YFKPBYRVSA-N
23592	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23593	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23594	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4330	3-[4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamino]-Phenol	-	-	DRUGBANK	DB04518	C15H14N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JJDRRZFRTKZLFT-UHFFFAOYSA-N
23655	110411	4255	RP11-109A6.1	MGMT	-	9606	Homo sapiens	unknown	target	Imming P (2006)	17016423	171742	4343	Benzylcysteine	-	-	DRUGBANK	DB04531	C10H13NO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GHBAYRBVXCRIHT-VIFPVBQESA-N
23656	110411	4255	RP11-109A6.1	MGMT	-	9606	Homo sapiens	unknown	target	Overington JP (2006)	17139284	171741	4343	Benzylcysteine	-	-	DRUGBANK	DB04531	C10H13NO2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GHBAYRBVXCRIHT-VIFPVBQESA-N
23767	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4416	PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE	-	-	DRUGBANK	DB04607	C20H14Cl2N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQAWGIKJINAKIZ-UHFFFAOYSA-N
23804	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4467	OLOMOUCINE II	-	-	DRUGBANK	DB04662	C19H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NDUVSANREQEDRE-CQSZACIVSA-N
23806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	4474	TRIAZOLOPYRIMIDINE	-	-	DRUGBANK	DB04669	C17H14BrN6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YWBFPKPWMSWWEA-UHFFFAOYSA-O
24042	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Maekawa T (2007)	17929114	182055	4668	Nilotinib	Nilotinibum	tasigna	DRUGBANK	DB04868	C28H22F3N7O	small molecule	L01XE08	641571-10-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHZIURLSWUIHRB-UHFFFAOYSA-N
24043	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Kantarjian HM (2007)	17715389	182041	4668	Nilotinib	Nilotinibum	tasigna	DRUGBANK	DB04868	C28H22F3N7O	small molecule	L01XE08	641571-10-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHZIURLSWUIHRB-UHFFFAOYSA-N
24044	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Weisberg E (2006)	16721371	181947	4668	Nilotinib	Nilotinibum	tasigna	DRUGBANK	DB04868	C28H22F3N7O	small molecule	L01XE08	641571-10-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHZIURLSWUIHRB-UHFFFAOYSA-N
24045	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Swords R (2009)	19920925	182135	4668	Nilotinib	Nilotinibum	tasigna	DRUGBANK	DB04868	C28H22F3N7O	small molecule	L01XE08	641571-10-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHZIURLSWUIHRB-UHFFFAOYSA-N
24046	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Rosti G (2009)	19822896	182130	4668	Nilotinib	Nilotinibum	tasigna	DRUGBANK	DB04868	C28H22F3N7O	small molecule	L01XE08	641571-10-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HHZIURLSWUIHRB-UHFFFAOYSA-N
24252	106825	328	-	APEX1	APE|APE1|APEN|APEX|APX|HAP1|REF1	9606	Homo sapiens	inhibitor	target	Luo M (2004)	15330152	181860	4759	Lucanthone	1-diethylaminoethylethylamino-4-methyl-thioxanthenone|Lucanthonum|Lucanthone|1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one|1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one|Lucantona	-	DRUGBANK	DB04967	C20H24N2OS	small molecule	-	479-50-5	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FBQPGGIHOFZRGH-UHFFFAOYSA-N
24588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor	target	Remsing Rix LL (2009)	19039322	182092	5562	Bosutinib	SKI 606|Bosulif|4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile|Bosutinib|SKI-606|Bosutinib Monohydrate|BDBM4552	bosulif	DRUGBANK	DB06616	C26H29Cl2N5O3	small molecule	L01XE14	380843-75-4	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UBPYILGKFZZVDX-UHFFFAOYSA-N
24870	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5665	4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE	-	-	DRUGBANK	DB06844	C21H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBXKBJLIESPLIK-UHFFFAOYSA-N
24880	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5673	4-[(3S)-1-AZABICYCLO[2.2.2]OCT-3-YLAMINO]-3-(1H-BENZIMIDAZOL-2-YL)-6-CHLOROQUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB06852	C23H22ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MOVBBVMDHIRCTG-LJQANCHMSA-N
24906	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5696	N-{5-[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}NICOTINAMIDE	-	-	DRUGBANK	DB06876	C24H24N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YJWJKKXGAPWLGT-UHFFFAOYSA-N
24917	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5708	(13R,15S)-13-METHYL-16-OXA-8,9,12,22,24-PENTAAZAHEXACYCLO[15.6.2.16,9.1,12,15.0,2,7.0,21,25]HEPTACOSA-1(24),2,4,6,17(25),18,20-HEPTAENE-23,26-DIONE	-	-	DRUGBANK	DB06888	C22H21N5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBLPHMRCKHFBJB-OLZOCXBDSA-N
24967	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5763	N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide	-	-	DRUGBANK	DB06944	C18H17N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RIGZCVNCFXYBEG-UHFFFAOYSA-N
24971	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5767	2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE	-	-	DRUGBANK	DB06948	C18H21N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XWWRLKIBRPJQJX-UHFFFAOYSA-N
24991	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5794	1-(5-OXO-2,3,5,9B-TETRAHYDRO-1H-PYRROLO[2,1-A]ISOINDOL-9-YL)-3-(5-PYRROLIDIN-2-YL-1H-PYRAZOL-3-YL)-UREA	-	-	DRUGBANK	DB06976	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IWOOJEZSDPRYAZ-WFASDCNBSA-N
24997	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5801	(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methanol	-	-	DRUGBANK	DB06983	C19H17N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RBLKWWBHDUBPFN-UHFFFAOYSA-N
25003	113220	7374	-	UNG	DGU|HIGM4|HIGM5|UDG|UNG1|UNG15|UNG2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5808	4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID	-	-	DRUGBANK	DB06990	C15H14N4O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XHDKIDMFBWLHAX-GONBZBRSSA-N
25037	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5842	2-(3,4-DIHYDROXYPHENYL)-8-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-3-HYDROXY-6-METHYL-4H-CHROMEN-4-ONE	-	-	DRUGBANK	DB07024	C19H17NO7S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CEXBEGBNDJVZPK-UHFFFAOYSA-N
25038	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5843	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)QUINOLIN-2(1H)-ONE	-	-	DRUGBANK	DB07025	C24H26N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KBIHHEGEALBUMT-UHFFFAOYSA-N
25047	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5852	2,2'-{[9-(HYDROXYIMINO)-9H-FLUORENE-2,7-DIYL]BIS(OXY)}DIACETIC ACID	-	-	DRUGBANK	DB07034	C17H13NO7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VOKATEXROYSXDW-UHFFFAOYSA-N
25049	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5855	(2S)-1-AMINO-3-[(5-NITROQUINOLIN-8-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07037	C12H14N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MBZPCTWLFNYBND-QMMMGPOBSA-N
25050	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5856	2-(cyclohexylamino)benzoic acid	-	-	DRUGBANK	DB07038	C13H17NO2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JSXMFCCPQQJLCR-UHFFFAOYSA-N
25060	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5872	(2R)-1-(DIMETHYLAMINO)-3-{4-[(6-{[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-4-YL)AMINO]PHENOXY}PROPAN-2-OL	-	-	DRUGBANK	DB07054	C22H23F4N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OSCWQKTUILTARV-MRXNPFEDSA-N
25069	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5883	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)-3-thiocyanatopyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07065	C19H12Cl2N6S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AHPKUZJCNHGFQA-UHFFFAOYSA-N
25079	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5893	3-(5-{[4-(AMINOMETHYL)PIPERIDIN-1-YL]METHYL}-1H-INDOL-2-YL)-1H-INDAZOLE-6-CARBONITRILE	-	-	DRUGBANK	DB07075	C23H24N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WBKUBPBCFYCSRT-UHFFFAOYSA-N
25082	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5896	(3Z)-6-(4-HYDROXY-3-METHOXYPHENYL)-3-(1H-PYRROL-2-YLMETHYLENE)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB07078	C20H16N2O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYSXURJZVXBSRV-WJDWOHSUSA-N
25108	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5914	6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE	-	-	DRUGBANK	DB07096	C12H8N2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SSMIFVHARFVINF-UHFFFAOYSA-N
25125	113220	7374	-	UNG	DGU|HIGM4|HIGM5|UDG|UNG1|UNG15|UNG2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5934	1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE	-	-	DRUGBANK	DB07116	C14H18NO6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UXXYPWCUINVUHL-BFHYXJOUSA-N
25134	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5944	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	-	-	DRUGBANK	DB07126	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWXORKPNCHJYOF-UHFFFAOYSA-N
25147	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5955	(2S)-N-[(3Z)-5-CYCLOPROPYL-3H-PYRAZOL-3-YLIDENE]-2-[4-(2-OXOIMIDAZOLIDIN-1-YL)PHENYL]PROPANAMIDE	-	-	DRUGBANK	DB07137	C18H19N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JPAWNIKVRIVDBT-PORMKJMCSA-N
25168	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5976	5-ETHYL-3-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]QUINOLIN-4-ONE	-	-	DRUGBANK	DB07158	C13H13N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ASEHARDUZDZEKS-UHFFFAOYSA-N
25173	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5981	5-[(2-AMINOETHYL)AMINO]-6-FLUORO-3-(1H-PYRROL-2-YL)BENZO[CD]INDOL-2(1H)-ONE	-	-	DRUGBANK	DB07163	C17H15FN4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CQCXWWWNUFQYJS-UHFFFAOYSA-N
25174	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5982	N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine	-	-	DRUGBANK	DB07164	C13H12N6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CAGHIASAHLPQMS-UHFFFAOYSA-N
25186	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	5996	3-((3-bromo-5-o-tolylpyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide	-	-	DRUGBANK	DB07179	C19H16BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DXUJQXZHHGJMFM-UHFFFAOYSA-N
25205	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6020	6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE	-	-	DRUGBANK	DB07203	C18H20ClN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OUEGMEMDEAOAEG-UHFFFAOYSA-N
25215	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6027	3-bromo-5-phenyl-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB07210	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JECHSYMSTXETFI-UHFFFAOYSA-N
25219	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6030	(5-{3-[5-(PIPERIDIN-1-YLMETHYL)-1H-INDOL-2-YL]-1H-INDAZOL-6-YL}-2H-1,2,3-TRIAZOL-4-YL)METHANOL	-	-	DRUGBANK	DB07213	C24H25N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FNWHPLLNMLOZTL-UHFFFAOYSA-N
25228	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6036	N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE	-	-	DRUGBANK	DB07220	C23H27N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZXYIRNXOAJYLCU-UHFFFAOYSA-N
25237	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6044	1-(5-CHLORO-2-METHOXYPHENYL)-3-{6-[2-(DIMETHYLAMINO)-1-METHYLETHOXY]PYRAZIN-2-YL}UREA	-	-	DRUGBANK	DB07228	C17H22ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GIAYFZLMPSVQDV-NSHDSACASA-N
25242	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6048	Veliparib	2-((2R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide|(2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium	-	DRUGBANK	DB07232	C13H16N4O	small molecule	-	912444-00-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
25243	115350	10038	-	PARP2	ADPRT2|ADPRTL2|ADPRTL3|ARTD2|PARP-2|pADPRT-2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6048	Veliparib	2-((2R)-2-methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide|(2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium	-	DRUGBANK	DB07232	C13H16N4O	small molecule	-	912444-00-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNAHVYVRKWKWKQ-CYBMUJFWSA-N
25245	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6050	3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	-	-	DRUGBANK	DB07234	C17H15N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MCBPNFWHHNJTGN-LLVKDONJSA-N
25253	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6059	(3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-PYRROLO[2,3-B]PYRIDINE-3-CARBOXYLATE	-	-	DRUGBANK	DB07243	C16H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQGFCATXRXQKNB-GDNZZTSVSA-N
25318	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6127	18-CHLORO-11,12,13,14-TETRAHYDRO-1H,10H-8,4-(AZENO)-9,15,1,3,6-BENZODIOXATRIAZACYCLOHEPTADECIN-2-ONE	-	-	DRUGBANK	DB07311	C16H17ClN4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRSWWYITYIOHOP-UHFFFAOYSA-N
25321	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6130	1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-CYANOPYRAZIN-2-YL)UREA	-	-	DRUGBANK	DB07314	C14H12ClN5O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	URQYPXQXSVUVRG-UHFFFAOYSA-N
25327	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6136	4-(6-{[(4-METHYLCYCLOHEXYL)AMINO]METHYL}-1,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)BENZOIC ACID	-	-	DRUGBANK	DB07320	C25H27N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEDLHZCDTXWLOC-SGNKCFNYSA-N
25336	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6146	trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium	-	-	DRUGBANK	DB07330	C16H22N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KXSIHXHEHABEJX-UHFFFAOYSA-N
25341	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6152	4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL	-	-	DRUGBANK	DB07336	C21H16N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GYPHGCGOSZJXOT-UHFFFAOYSA-N
25431	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6220	(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE	-	-	DRUGBANK	DB07406	C21H24N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QWFFPYQWUWLDBV-NSHDSACASA-N
25451	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6243	(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	-	-	DRUGBANK	DB07430	C21H18N4OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CMWRPDHVGMHLSZ-GFCCVEGCSA-N
25452	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6244	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	-	-	DRUGBANK	DB07431	C13H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXYKBKYDFZQOCB-SSDOTTSWSA-N
25453	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6244	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	-	-	DRUGBANK	DB07431	C13H15N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TXYKBKYDFZQOCB-SSDOTTSWSA-N
25455	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6248	1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE	-	-	DRUGBANK	DB07435	C20H16O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GFANZDFKCCJYRF-NSISKUIASA-N
25484	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6282	5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE	-	-	DRUGBANK	DB07471	C22H20ClN3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UHCHLTQBLNUYRT-GFCCVEGCSA-N
25503	111419	5423	-	POLB	-	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6290	(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL	-	-	DRUGBANK	DB07479	C18H16O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCUHTHVUZQCBTI-KBAYOESNSA-N
25516	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6304	(2Z)-5'-BROMO-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE AMMONIATE	-	-	DRUGBANK	DB07493	C16H9BrN2O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IEQQJQHHJMQETK-YPKPFQOOSA-N
25523	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6312	(2S)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07501	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-KRWDZBQOSA-N
25526	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6315	(2R)-1-{4-[(4-ANILINO-5-BROMOPYRIMIDIN-2-YL)AMINO]PHENOXY}-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07504	C21H24BrN5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEIJADBULOETOV-QGZVFWFLSA-N
25543	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6339	2-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONE	-	-	DRUGBANK	DB07529	C9H7N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LHGOQMPIWSCKBA-FNORWQNLSA-N
25546	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6341	4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07531	C14H10N2O5S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JNPRTUHVCHGFHJ-GHXNOFRVSA-N
25547	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6343	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07533	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FJJJERLTHDXEPT-JYRVWZFOSA-N
25549	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6344	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07534	C14H11N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKUMVXIXUVYKDQ-GHXNOFRVSA-N
25553	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6348	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07538	C15H10F3N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RGVVHQNJKUNSFQ-WDZFZDKYSA-N
25555	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6349	4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID	-	-	DRUGBANK	DB07539	C15H10N2O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JLRKRQCTYQGDKJ-GHXNOFRVSA-N
25557	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6350	4-{5-[(1Z)-1-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ETHYL]-2-FURYL}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07540	C15H13N3O4S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AKFVRSQELXTCFW-JYRVWZFOSA-N
25577	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6371	N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE	-	-	DRUGBANK	DB07562	C17H19N5S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FGGSNQOBRJVAKL-UHFFFAOYSA-N
25605	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6402	(5Z)-5-(3-BROMOCYCLOHEXA-2,5-DIEN-1-YLIDENE)-N-(PYRIDIN-4-YLMETHYL)-1,5-DIHYDROPYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE	-	-	DRUGBANK	DB07595	C18H15BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WSIQKQLAGWVKSL-UHFFFAOYSA-O
25613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6412	6-(3,4-DIHYDROXYBENZYL)-3-ETHYL-1-(2,4,6-TRICHLOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4(5H)-ONE	-	-	DRUGBANK	DB07606	C20H15Cl3N4O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OPRAIFVPXXVXDL-UHFFFAOYSA-N
25617	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6418	6-(3-AMINOPHENYL)-N-(TERT-BUTYL)-2-(TRIFLUOROMETHYL)QUINAZOLIN-4-AMINE	-	-	DRUGBANK	DB07612	C19H19F3N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XQKJVNGGVLHNLA-UHFFFAOYSA-N
25623	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6424	2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE	-	-	DRUGBANK	DB07618	C24H31N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AITZHKQVQNLKHI-UHFFFAOYSA-N
25626	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6428	1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA	-	-	DRUGBANK	DB07622	C21H23N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KRKQVGZXTNLQSV-UHFFFAOYSA-N
25653	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6453	(2R)-1-[(5,6-DIPHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PROPAN-2-OL	-	-	DRUGBANK	DB07647	C21H20N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VBASHTSSQNDDAS-CQSZACIVSA-N
25654	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6454	(2R)-3-{[(4Z)-5,6-DIPHENYL-6,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-YLIDENE]AMINO}PROPANE-1,2-DIOL	-	-	DRUGBANK	DB07648	C21H20N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TWEONIHFGKSPLC-MRXNPFEDSA-N
25656	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6458	1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE	-	-	DRUGBANK	DB07652	C12H15F2O6P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMMWBGNJJMNAIJ-QJPTWQEYSA-N
25657	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6459	N-(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)GLYCINE	-	-	DRUGBANK	DB07653	C20H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VXTCEUDVOCLEJG-UHFFFAOYSA-N
25658	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6460	(5,6-DIPHENYL-FURO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC	-	-	DRUGBANK	DB07654	C21H19N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VDJWWYRYKMXMKA-UHFFFAOYSA-N
25659	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6461	3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE	-	-	DRUGBANK	DB07655	C20H18N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MPJYGQHMIFDQIN-UHFFFAOYSA-N
25685	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6483	2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one	-	-	DRUGBANK	DB07677	C8H10N2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HRYKZAKEAVZGJD-UHFFFAOYSA-N
25692	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6490	4-{[5-(CYCLOHEXYLMETHOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07685	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMAZGYDYIYLSLJ-UHFFFAOYSA-N
25693	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6491	4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07686	C17H21N7O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VPOGRVWIIVMWRI-UHFFFAOYSA-N
25694	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6492	4-({5-[(4-AMINOCYCLOHEXYL)AMINO][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07687	C17H22N8O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LVRKQJAEQWVSCM-HAQNSBGRSA-N
25695	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6493	4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB07688	C17H20N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPJIMTALCNCQLV-UHFFFAOYSA-N
25733	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6529	2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB07728	C18H14FN3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	XJJYJNMNYDNXNO-UHFFFAOYSA-N
25736	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6532	4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL	-	-	DRUGBANK	DB07731	C9H10N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AYZRKFOEZQBUEA-OUKQBFOZSA-N
25751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6551	(2R)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07750	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-MRXNPFEDSA-N
25752	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6552	(2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07751	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-HNNXBMFYSA-N
25763	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6556	(2S)-1-[4-({4-[(2,5-DICHLOROPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07755	C21H23Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GNLAGGCSJGJECE-INIZCTEOSA-N
25768	113220	7374	-	UNG	DGU|HIGM4|HIGM5|UDG|UNG1|UNG15|UNG2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6561	3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid	-	-	DRUGBANK	DB07760	C15H14N4O6	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUYDQQMKXSQIQG-GONBZBRSSA-N
25769	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6562	(2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL	-	-	DRUGBANK	DB07761	C21H23F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZVSBKYYVBCKDBO-OAHLLOKOSA-N
25815	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6586	5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE	-	-	DRUGBANK	DB07787	C23H24FN3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PNPFDRCIGCUCMN-UHFFFAOYSA-N
25818	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6589	N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE	-	-	DRUGBANK	DB07790	C20H26N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LDXLQEXLXZCYSR-UHFFFAOYSA-N
25819	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6590	4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE	-	-	DRUGBANK	DB07791	C18H20N6O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MZWCVBFANHIPTJ-UHFFFAOYSA-N
25849	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6628	2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE	-	-	DRUGBANK	DB07831	C23H22F3N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SHSORWZDEKFFLP-UHFFFAOYSA-N
25876	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6649	1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID	-	-	DRUGBANK	DB07852	C10H7Cl2N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CZTNDZALWLHXBA-UHFFFAOYSA-N
25919	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6686	1-(DIMETHYLAMINO)-3-(4-{{4-(2-METHYLIMIDAZO[1,2-A]PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PHENOXY)PROPAN-2-OL	-	-	DRUGBANK	DB07889	C23H26N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	VCPXSBULBDYRLT-SFHVURJKSA-N
25964	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6732	N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine	-	-	DRUGBANK	DB07936	C24H30FN7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BACSZMCLZIDTIO-IBGZPJMESA-N
25991	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6754	3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE	-	-	DRUGBANK	DB07959	C14H10N4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JTKFRFMSUBOCIQ-UHFFFAOYSA-N
26009	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6777	2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol	-	-	DRUGBANK	DB07982	C23H29N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PVTKDXZNSUHUMO-UHFFFAOYSA-N
26063	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6836	1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA	-	-	DRUGBANK	DB08043	C19H14F3N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DDDLGNOZDKDSEG-UHFFFAOYSA-N
26079	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6851	4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one	-	-	DRUGBANK	DB08058	C21H21FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGEPGGJUGUMFHT-UHFFFAOYSA-N
26092	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6859	N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE	-	-	DRUGBANK	DB08066	C17H13N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPKSFXFWECAIBR-UHFFFAOYSA-N
26122	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6887	(4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE	-	-	DRUGBANK	DB08094	C18H21F2N5O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JRNJNYBQQYBCLE-UHFFFAOYSA-N
26141	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6914	N-METHYL-4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE	-	-	DRUGBANK	DB08122	C16H15N3O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IKASAFLVQIJQOK-UVTDQMKNSA-N
26142	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6915	N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE	-	-	DRUGBANK	DB08123	C17H15N5O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GEWPSTLKJDIUHW-UHFFFAOYSA-N
26143	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6916	3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE	-	-	DRUGBANK	DB08124	C20H15N3O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FTQYGMLRLRXBPT-IDUWFGFVSA-N
26144	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6917	4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE	-	-	DRUGBANK	DB08125	C18H14N4O3S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BOMPRXSVSIPRDT-PTNGSMBKSA-N
26145	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6918	3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE	-	-	DRUGBANK	DB08126	C16H15N5O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DMCRNUMVSATRTP-LCYFTJDESA-N
26150	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6924	5-hydroxynaphthalene-1-sulfonamide	-	-	DRUGBANK	DB08132	C10H9NO3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NFVBVKHGDDDCEA-UHFFFAOYSA-N
26151	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6925	N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide	-	-	DRUGBANK	DB08133	C14H12N4O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MNHPHKFLWAPNOV-UHFFFAOYSA-N
26152	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6926	4-[(6-chloropyrazin-2-yl)amino]benzenesulfonamide	-	-	DRUGBANK	DB08134	C10H9ClN4O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RSNSGNZRUMHXAY-UHFFFAOYSA-N
26153	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6927	N-phenyl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08135	C10H9N3O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WMZYZYFPPQOFKY-UHFFFAOYSA-N
26154	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6928	4-(acetylamino)-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08136	C12H11FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CWQKPKYIMQTGJK-UHFFFAOYSA-N
26155	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6929	(4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08137	C17H13FN4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZMWYSLJBNJUCRK-UHFFFAOYSA-N
26156	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6930	{[(2,6-difluorophenyl)carbonyl]amino}-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08138	C17H11F3N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BDRDBXXWQDFXEC-UHFFFAOYSA-N
26157	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6931	5-chloro-7-[(1-methylethyl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile	-	-	DRUGBANK	DB08139	C10H10ClN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HFTLYNKTSANXFA-UHFFFAOYSA-N
26158	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6932	5-[(4-AMINOCYCLOHEXYL)AMINO]-7-(PROPAN-2-YLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBONITRILE	-	-	DRUGBANK	DB08140	C16H23N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FOESVLPZMGVWBM-JOCQHMNTSA-N
26159	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6933	4-{[(2,6-difluorophenyl)carbonyl]amino}-N-[(3S)-piperidin-3-yl]-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08141	C16H17F2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KOMNQBZWMCFDTQ-VIFPVBQESA-N
26160	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6934	4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamide	-	-	DRUGBANK	DB08142	C16H17Cl2N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OVPNQJVDAFNBDN-UHFFFAOYSA-N
26203	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6970	4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08178	C12H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GGEWEQJWGGJUHO-UHFFFAOYSA-N
26208	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	6974	4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine	-	-	DRUGBANK	DB08182	C14H15N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZHMRPXZRUZLCNL-UHFFFAOYSA-N
26234	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7009	HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM	-	-	DRUGBANK	DB08218	C19H15N7O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PLQVWKCQWFFUFJ-FCDQGJHFSA-N
26236	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7010	4-METHYL-5-{(2E)-2-[(4-MORPHOLIN-4-YLPHENYL)IMINO]-2,5-DIHYDROPYRIMIDIN-4-YL}-1,3-THIAZOL-2-AMINE	-	-	DRUGBANK	DB08219	C18H20N6OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RPSZSAKYXPWBRR-RELWKKBWSA-N
26262	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7021	MYRISTIC ACID	-	-	DRUGBANK	DB08231	C14H28O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	TUNFSRHWOTWDNC-UHFFFAOYSA-N
26273	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7023	6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE	-	-	DRUGBANK	DB08233	C18H21N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RFSDQDHHBKYQOD-UHFFFAOYSA-N
26290	119532	51426	-	POLK	DINB1|DINP|POLQ	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7027	2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)	-	-	DRUGBANK	DB08237	C21H22N5O7P	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	COMPKRGNHXOXMN-GVDBMIGSSA-N
26294	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7031	4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE	-	-	DRUGBANK	DB08241	C19H22N6O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RUUOIINPNMNPIU-UHFFFAOYSA-N
26299	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7036	6-(CYCLOHEXYLMETHOXY)-8-ISOPROPYL-9H-PURIN-2-AMINE	-	-	DRUGBANK	DB08247	C15H23N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	JABXNQUXGJTKRO-UHFFFAOYSA-N
26300	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7037	3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE	-	-	DRUGBANK	DB08248	C18H22N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BKDUVKJYBJDZQW-UHFFFAOYSA-N
26325	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7073	(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol	-	-	DRUGBANK	DB08285	C19H26N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SQUNOCMDMIQIQK-OAHLLOKOSA-N
26346	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7096	3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL	-	-	DRUGBANK	DB08309	C23H32N6O4S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AMFGILNPFBVREA-UHFFFAOYSA-N
26348	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7098	6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE	-	-	DRUGBANK	DB08312	C11H17N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	DGWXOLHKVGDQLN-UHFFFAOYSA-N
26381	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7125	6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE	-	-	DRUGBANK	DB08339	C21H16Cl2N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZIQFYVPVJZEOFS-UHFFFAOYSA-N
26394	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7133	N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE	-	-	DRUGBANK	DB08348	C17H17N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UYJZZVDLGDDTCL-UHFFFAOYSA-N
26397	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7135	5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08350	C22H20N4O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	GYQRHHQPEMOLKH-UHFFFAOYSA-N
26402	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7140	1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid	-	-	DRUGBANK	DB08355	C17H15N5O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZOBRPBVIEUWYJR-UHFFFAOYSA-N
26407	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7143	2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	-	-	DRUGBANK	DB08358	C21H16N4O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OWFLADWRSCINST-UHFFFAOYSA-N
26437	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7176	2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL	-	-	DRUGBANK	DB08392	C22H21N3O4	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ARBUGBBNEFAECO-UHFFFAOYSA-N
26438	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7177	2-[(5,6-DIPHENYLFURO[2,3-D]PYRIMIDIN-4-YL)AMINO]ETHANOL	-	-	DRUGBANK	DB08393	C20H17N3O2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	UQHINZSKNAAVOZ-UHFFFAOYSA-N
26492	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7223	6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE	-	-	DRUGBANK	DB08441	C13H14BrN5O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	AWSQADBSXFTFKL-UHFFFAOYSA-N
26514	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7244	(2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol	-	-	DRUGBANK	DB08463	C24H29N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HOCBJBNQIQQQGT-LJQANCHMSA-N
26575	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7305	1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE	-	-	DRUGBANK	DB08527	C15H12N6O3S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HGAKLLFPOGATII-UHFFFAOYSA-N
26579	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7309	5-(2,3-dichlorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08531	C18H13Cl2N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CVYWYUAQFJMLEO-UHFFFAOYSA-N
26580	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7310	6-(2-fluorophenyl)-N-(pyridin-3-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08532	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WCNPGRRMPFCHEO-UHFFFAOYSA-N
26581	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7311	3-methyl-N-(pyridin-4-ylmethyl)imidazo[1,2-a]pyrazin-8-amine	-	-	DRUGBANK	DB08533	C13H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LXRVAGIYXNQOKP-UHFFFAOYSA-N
26582	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7312	5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08534	C18H14FN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	ZAIYYXVHGBMLEC-UHFFFAOYSA-N
26583	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7313	3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08535	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	SMIZFGZXFDGISG-UHFFFAOYSA-N
26584	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7314	3-bromo-5-phenyl-N-(pyrimidin-5-ylmethyl)pyrazolo[1,5-a]pyridin-7-amine	-	-	DRUGBANK	DB08536	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	IBUPHWYGVDAASU-UHFFFAOYSA-N
26585	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7315	3-bromo-6-phenyl-N-(pyrimidin-5-ylmethyl)imidazo[1,2-a]pyridin-8-amine	-	-	DRUGBANK	DB08537	C18H14BrN5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LZLKFNBMXXLTLX-UHFFFAOYSA-N
26586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7316	N-((2-aminopyrimidin-5-yl)methyl)-5-(2,6-difluorophenyl)-3-ethylpyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08538	C19H17F2N7	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HQPVGVSQPQVZLD-UHFFFAOYSA-N
26587	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7317	3-cyclopropyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine	-	-	DRUGBANK	DB08539	C21H19N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	CCDIUVLNHCGSMH-UHFFFAOYSA-N
26613	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7349	4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE	-	-	DRUGBANK	DB08572	C18H22N6O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBKLJTXDSBEVRV-UHFFFAOYSA-N
26619	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7360	2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide	-	-	DRUGBANK	DB08583	C21H22N6O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	INAGORZAOFUKOZ-UHFFFAOYSA-N
26684	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7447	4-[(5-ISOPROPYL-1,3-THIAZOL-2-YL)AMINO]BENZENESULFONAMIDE	-	-	DRUGBANK	DB08673	C12H15N3O2S2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	LPQUJAANWFHCJV-UHFFFAOYSA-N
26690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7451	N-(5-ISOPROPYL-THIAZOL-2-YL)-2-PYRIDIN-3-YL-ACETAMIDE	-	-	DRUGBANK	DB08677	C13H15N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	WQZOOPQQADNJEG-UHFFFAOYSA-N
26692	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7457	REL-(9R,12S)-9,10,11,12-TETRAHYDRO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-1,3(2H)-DIONE	-	-	DRUGBANK	DB08683	C24H15N3O3	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OTPNDVKVEAIXTI-IYBDPMFKSA-N
26721	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7468	9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol	-	-	DRUGBANK	DB08694	C14H11N7O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	RTHKPHCVZVYDFN-UHFFFAOYSA-N
26768	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7541	N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE	-	-	DRUGBANK	DB08768	C10H13N5	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	HYVABZIGRDEKCD-UHFFFAOYSA-N
26775	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7546	1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine	-	-	DRUGBANK	DB08774	C17H19N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	YBRZCAKSBYWZTC-ZDUSSCGKSA-N
26777	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7548	N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE	-	-	DRUGBANK	DB08776	C9H11N3O2S	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	OYHOEDBNAJPFKK-UHFFFAOYSA-N
26778	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7549	5,6,7,8-TETRAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE	-	-	DRUGBANK	DB08777	C10H10N2OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	NMMOEJUJKIXUQZ-UHFFFAOYSA-N
26779	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7550	[4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone	-	-	DRUGBANK	DB08778	C14H17N3OS	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KEHNGAHNKVLUSC-UHFFFAOYSA-N
26780	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7551	2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol	-	-	DRUGBANK	DB08779	C9H10N2OS2	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	QWYGHJVEZLVLSU-UHFFFAOYSA-N
26781	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7552	6-MORPHOLIN-4-YL-9H-PURINE	-	-	DRUGBANK	DB08780	C9H11N5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	MEOMXKNIFWDDGZ-UHFFFAOYSA-N
26782	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	unknown	target	Berman HM (2000)	10592235	172122	7553	1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE	-	-	DRUGBANK	DB08781	C11H14BrN5O	small molecule	-	-	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	BJUBFXSKTBULRW-ZETCQYMHSA-N
26870	107169	708	-	C1QBP	GC1QBP|HABP1|SF2p32|gC1Q-R|gC1qR|p32	9606	Homo sapiens	binder	target	Yadav G (2009)	19004836	182090	7587	Hyaluronic acid	Hyaluronan|Hyaluronate	wellage family mask small|deep	DRUGBANK	DB08818	C28H44N2O23	small molecule	S01KA01|M09AX01|S01KA51|D03AX05|R01AX09	9004-61-9	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	KIUKXJAPPMFGSW-MNSSHETKSA-N
26966	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	inhibitor	target	Iqbal Z (2013)	23409026	182230	7645	Ponatinib	AP24534|AP 24534|Ponatinibum	iclusig	DRUGBANK	DB08901	C29H27F3N6O	small molecule	L01XE24	943319-70-8	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	PHXJVRSECIGDHY-UHFFFAOYSA-N
27479	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	inhibitor	target	Verhagen CV (2015)	25981132	188550	7821	Olaparib	4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one	lynparza	DRUGBANK	DB09074	-	small molecule	L01XX46	763113-22-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27480	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	inhibitor	target	Verhagen CV (2015)	25981132	188550	7821	Olaparib	4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one	lynparza	DRUGBANK	DB09074	-	small molecule	L01XX46	763113-22-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27481	115350	10038	-	PARP2	ADPRT2|ADPRTL2|ADPRTL3|ARTD2|PARP-2|pADPRT-2	9606	Homo sapiens	inhibitor	target	Verhagen CV (2015)	25981132	188550	7821	Olaparib	4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one	lynparza	DRUGBANK	DB09074	-	small molecule	L01XX46	763113-22-0	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	-
27693	123818	83933	RP3-402G11.7	HDAC10	HD10	9606	Homo sapiens	inhibitor	target	Beckers T (2007)	17455259	182004	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
27861	123818	83933	RP3-402G11.7	HDAC10	HD10	9606	Homo sapiens	inhibitor	target	Geng L (2006)	17145876	195973	8079	Panobinostat	(2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide|panobinostat|BDBM29589	farydak	DRUGBANK	DB06603	C21H23N3O2	small molecule	L01XX42	404950-80-7	DRUGBANK	-	-	-	-	-	-	-	-	-	-	-	FPOHNWQLNRZRFC-ZHACJKMWSA-N
28022	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	degradation	recruited E3 ligase	Ohoka N (2014)	25375378	206180	8422	Bivalent ligand 5	Bivalent_ligand_5|SNIPER(TACC3)-1/SNIPER(TACC3)-2|SNIPER(TACC3)-1|SNIPER(TACC3)-2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	SNIPER	Specific and Non-genetic Inhibitor-of-apoptosis proteins (IAPs)-dependent Protein Eraser; structured as IAP ligand--linker--target binding moiety; target degraded via UPS	115723	10460	-	TACC3	ERIC-1|ERIC1	9606	Homo sapiens	target	Standardized BVL Name: SNIPER(TACC3)-1(cIAP1:bestatin --- TACC3:KHS108)	-
28035	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Lai AC (2016)	26593377	191787	8449	Bivalent ligand 11	Bivalent_ligand_11|DAS-VHL	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: DAS-VHL(VHL:HIF-1alpha hydroxyproline derived small molecule --- c-ABL:dasatinib)	-
28037	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Lai AC (2016)	26593377	191787	8452	Bivalent ligand 12	Bivalent_ligand_12|DAS-CRBN	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: DAS-CRBN(CRBN:pomalidomide --- BCR-ABL:dasatinib)	-
28039	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Lai AC (2016)	26593377	191787	8402	Bivalent ligand 43	Bivalent_ligand_43|BOS-CRBN	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: BOS-CRBN(CRBN:pomalidomide --- BCR-ABL:bosutinib)	-
28041	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Demizu Y (2016)	27666635	199362	8451	Bivalent ligand 13	Bivalent_ligand_13|SNIPER(ABL)2,3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106826	329	-	BIRC2	API1|HIAP2|Hiap-2|MIHB|RNF48|c-IAP1|cIAP1	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(ABL)2,3(cIAP1:methyl bestatin --- BCR-ABL:imatinib derivative)	-
28047	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Raina K (2016)	27274052	211416	8446	Bivalent ligand 14	Bivalent_ligand_14|ARV-771	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: ARV-771(VHL:HIF-1alpha hydroxyproline derived small molecule --- BRD4:triazolo-diazepine acetamide BET-binding moiety)	-
28053	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zengerle M (2015)	26035625	185990	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28055	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Winter GE (2015)	25999370	211411	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28057	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Lu J (2015)	26051217	211422	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28079	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ohoka N (2017)	28154167	211362	8416	Bivalent ligand 24	Bivalent_ligand_24|SNIPER(BRD4)-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(BRD4)-1(XIAP:LCL161 --- BRD4:JQ1)	-
28081	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Ohoka N (2017)	28154167	211362	8417	Bivalent ligand 25	Bivalent_ligand_25|SNIPER(ABL)-38	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	106828	331	RP1-315G1.5	XIAP	API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: SNIPER(ABL)-38(XIAP:LCL161 --- BCR-ABL:dasatinib)	-
28135	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhang X (2018)	29581547	211371	8443	Bivalent ligand 57	Bivalent_ligand_57|ARV-763	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: ARV-763 (VHL: :HIF-1alpha hydroxyproline derived small molecule --- BRD4:OTX015)	-
28137	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Robb CM (2017)	28636052	211400	8444	Bivalent ligand 56	Bivalent_ligand_56|PROTAC 3	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC 3(CRBN:thalidomide --- CDK9:aminopyrazole analog)	-
28155	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Winter GE (2017)	28673542	211369	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: dBET6(CRBN:thalidomide --- BRD4:JQ1)	-
28159	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Gadd MS (2017)	28288108	210014	8430	Bivalent ligand 62	Bivalent_ligand_62|AT-1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: AT-1 (VHL:modified VH032 --- BRD4:JQ1)	-
28195	114837	9447	RP11-520H16.3	AIM2	PYHIN4	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- AIM2:foretinib)	-
28197	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- MAPKAPK2:foretinib)	-
28215	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- ABL1:foretinib)	-
28259	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited E3 ligase	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ABL1:foretinib)	-
28346	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Boselli M (2017)	28972160	211413	8325	IU1-47	Ethanone, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)-|1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-piperidinyl)ethanone	-	CHEMSPIDER	588237	C19H23ClN2O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VXQIPRWKLACSKZ-UHFFFAOYSA-N
28347	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Zhao C (2017)	28086217	211382	8326	ZnPT, zinc pyrithione	Pyrithione zinc|Zinc bis(pyridine-2-thiolate 1-oxide)|2295|R953O2RHZ5|2-Pyridinethiol, 1-oxide, zinc salt (2:1)|Zinc bis(2-pyridinethiolate 1-oxide)	-	CHEMSPIDER	24255	C10H8N2O2S2Zn	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTPSWLRZXRHDNX-UHFFFAOYSA-L
28348	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Zhao C (2017)	28086217	211382	8326	ZnPT, zinc pyrithione	Pyrithione zinc|Zinc bis(pyridine-2-thiolate 1-oxide)|2295|R953O2RHZ5|2-Pyridinethiol, 1-oxide, zinc salt (2:1)|Zinc bis(2-pyridinethiolate 1-oxide)	-	CHEMSPIDER	24255	C10H8N2O2S2Zn	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OTPSWLRZXRHDNX-UHFFFAOYSA-L
28349	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28350	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28351	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28352	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2015)	25854145	187298	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28354	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28355	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Kapuria V (2010)	21045142	211373	8329	WP1130	2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)-|(2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]acrylamide|MFCD18839228	-	CHEMSPIDER	9397884	C19H18BrN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LIDOPKHSVQTSJY-VMEIHUARSA-N
28358	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	8330	GW7647	GW7647|Propanoic acid, 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methyl-|2-[(4-{2-[(4-Cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid	-	CHEMSPIDER	2637470	C29H46N2O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PKNYXWMTHFMHKD-UHFFFAOYSA-N
28359	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	8330	GW7647	GW7647|Propanoic acid, 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methyl-|2-[(4-{2-[(4-Cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid	-	CHEMSPIDER	2637470	C29H46N2O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PKNYXWMTHFMHKD-UHFFFAOYSA-N
28360	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	1088	Pimozide	Orap|Halomonth|Pimozida|Pimozide|Opiran|Pimozidum|Neoperidole	orap|pms-pimozide|orap tab 10m	DRUGBANK	DB01100	C28H29F2N3O	small molecule	N05AG02	2062-78-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YVUQSNJEYSNKRX-UHFFFAOYSA-N
28361	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	1088	Pimozide	Orap|Halomonth|Pimozida|Pimozide|Opiran|Pimozidum|Neoperidole	orap|pms-pimozide|orap tab 10m	DRUGBANK	DB01100	C28H29F2N3O	small molecule	N05AG02	2062-78-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YVUQSNJEYSNKRX-UHFFFAOYSA-N
28362	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Dexheimer TS (2014)	25229643	211355	8331	ML323	ML323|N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine|4-Pyrimidinamine, 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-|2-(2-Isopropylphenyl)-5-methyl-N-[4-(1H-1,2,3-triazol-1-yl)benzyl]-4-pyrimidinamine	-	CHEMSPIDER	30646677	C23H24N6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VUIRVWPJNKZOSS-UHFFFAOYSA-N
28363	121649	57599	-	WDR48	P80|SPG60|UAF1	9606	Homo sapiens	inhibitor	target	Dexheimer TS (2014)	25229643	211355	8331	ML323	ML323|N-(4-(1H-1,2,3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine|4-Pyrimidinamine, 5-methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-|2-(2-Isopropylphenyl)-5-methyl-N-[4-(1H-1,2,3-triazol-1-yl)benzyl]-4-pyrimidinamine	-	CHEMSPIDER	30646677	C23H24N6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VUIRVWPJNKZOSS-UHFFFAOYSA-N
28364	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Pozhidaeva A (2017)	29056420	211409	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28365	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Pozhidaeva A (2017)	29056420	211409	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28366	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Tian Z (2014)	24319254	211391	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28367	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Tian Z (2014)	24319254	211391	8328	b-AP15	(3E,5E)-1-Acryloyl-3,5-bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propen-1-yl)-, (3E,5E)-|(3E,5E)-1-acryloyl-3,5-bis(4-nitrobenzylidene)piperidin-4-one	-	CHEMSPIDER	4508454	C22H17N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFARQYQBWJLZMW-JYFOCSDGSA-N
28368	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	An T (2017)	28216017	211393	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
28369	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang X (2016)	27264969	211363	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28370	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Wang X (2016)	27264969	211363	8327	VLX1570	4H-Azepin-4-one, 3,5-bis[(4-fluoro-3-nitrophenyl)methylene]hexahydro-1-(1-oxo-2-propen-1-yl)-, (3Z,5Z)-|(3Z,5Z)-1-Acryloyl-3,5-bis(4-fluoro-3-nitrobenzylidene)-4-azepanone	-	CHEMSPIDER	57373743	C23H17F2N3O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SCKXBVLYWLLALY-CQRYCMKKSA-N
28371	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Lee BH (2010)	20829789	211386	8335	IU1	1-[1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)ethanone|Ethanone, 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-	-	CHEMSPIDER	588197	C18H21FN2O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JUWDSDKJBMFLHE-UHFFFAOYSA-N
28375	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Reverdy C (2012)	22520753	131069	8338	HBX 19818	2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-|N-{3-[Benzyl(methyl)amino]propyl}-9-chloro-5,6,7,8-tetrahydro-2-acridinecarboxamide	-	CHEMSPIDER	30814431	C25H28ClN3O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZCALMLVWZSQGGR-UHFFFAOYSA-N
28376	115508	10213	-	PSMD14	PAD1|POH1|RPN11	9606	Homo sapiens	inhibitor	target	Li J (2017)	28244987	211399	8339	Capzimin	8-Sulfanyl-N-[2-(1,3-thiazol-2-yl)ethyl]-3-quinolinecarboxamide|3-Quinolinecarboxamide, 8-mercapto-N-[2-(2-thiazolyl)ethyl]-	-	CHEMSPIDER	61729338	C15H13N3OS2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MYNGHZGMRXNEEH-UHFFFAOYSA-N
28381	113182	7334	-	UBE2N	HEL-S-71|UBC13|UBCHBEN; UBC13|UbcH-ben|UbcH13	9606	Homo sapiens	inhibitor	target	Hodge CD (2015)	25909880	186087	8343	NSC697923	2-[(4-Methylphenyl)sulfonyl]-5-nitrofuran|Furan, 2-[(4-methylphenyl)sulfonyl]-5-nitro-	-	CHEMSPIDER	349633	C11H9NO5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GAUHIPWCDXOLCZ-UHFFFAOYSA-N
28382	113182	7334	-	UBE2N	HEL-S-71|UBC13|UBCHBEN; UBC13|UbcH-ben|UbcH13	9606	Homo sapiens	inhibitor	target	Hodge CD (2015)	25909880	186087	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28403	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	modulator	target	Huang HL (2012)	22389469	211417	8359	Oridonin	Oridonin|(1alpha,5beta,6beta,7alpha,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-Tetrahydroxy-7,20-epoxykaur-16-en-15-one	-	CHEMSPIDER	23326877	C20H28O6	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	SDHTXBWLVGWJFT-BAFGBBEMSA-N
28440	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Tang Y (2017)	28807012	211380	8385	HBX 41,108	7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile|9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 7-chloro-9-oxo-	-	CHEMSPIDER	17225370	C13H3ClN4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BIGPXXAUSQLTQR-UHFFFAOYSA-N
28445	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Chen X (2018)	29098502	211361	8388	Pyrithione cadmium	Cadmium bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, cadmium salt (2:1)	-	CHEMSPIDER	178371	C10H8CdN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YSWAWAYOPDDQJN-UHFFFAOYSA-N
28446	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Chen X (2018)	29098502	211361	8388	Pyrithione cadmium	Cadmium bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, cadmium salt (2:1)	-	CHEMSPIDER	178371	C10H8CdN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YSWAWAYOPDDQJN-UHFFFAOYSA-N
28447	115508	10213	-	PSMD14	PAD1|POH1|RPN11	9606	Homo sapiens	inhibitor	target	Song Y (2017)	28581522	211353	2270	1,10-Phenanthroline	-	-	DRUGBANK	DB02365	C12H8N2	small molecule	-	66-71-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DGEZNRSVGBDHLK-UHFFFAOYSA-N
28448	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28452	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28456	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28457	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28461	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Altun M (2011)	22118674	126534	8389	PR-619	2,6-diamino-5-(cyanothio)pyridin-3-yl thiocyanate|2,6-Diamino-3,5-pyridinediyl bis(thiocyanate)|Thiocyanic acid, 2,6-diamino-3,5-pyridinediyl ester	-	CHEMSPIDER	2096054	C7H5N5S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZXOBLNBVNROVLC-UHFFFAOYSA-N
28463	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24977961	211418	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
28464	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24977961	211418	985	Auranofin	Auranofinum|Triethylphosphine gold|2,3,4,6-Tetra-O-acetyl-1-thio-beta-D-glucopyranosato-S (triethylphosphine)gold|(1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold 2,3,4,6-tetraacetate|Auranofine|Ridaura|Auranofina|Auroafen	ridaura	DRUGBANK	DB00995	C20H34AuO9PS	small molecule	M01CB03	34031-32-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AUJRCFUBUPVWSZ-XTZHGVARSA-M
28465	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Coughlin K (2014)	24727327	211407	8390	RA-9	(3E,5E)-3,5-Bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (3E,5E)-|(3E,5E)-3,5-bis(4-nitrobenzylidene)piperidin-4-one|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (E,E)-|NSC685125|(3E,5E)-3,5-Bis[(4-nitrophenyl)methylidene]piperidin-4-one	-	CHEMSPIDER	4579802	C19H15N3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YUYPWAMLWZVHAE-KAVGSWPWSA-N
28466	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Coughlin K (2014)	24727327	211407	8390	RA-9	(3E,5E)-3,5-Bis(4-nitrobenzylidene)-4-piperidinone|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (3E,5E)-|(3E,5E)-3,5-bis(4-nitrobenzylidene)piperidin-4-one|4-Piperidinone, 3,5-bis[(4-nitrophenyl)methylene]-, (E,E)-|NSC685125|(3E,5E)-3,5-Bis[(4-nitrophenyl)methylidene]piperidin-4-one	-	CHEMSPIDER	4579802	C19H15N3O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YUYPWAMLWZVHAE-KAVGSWPWSA-N
28467	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Tian X (2011)	21133675	211365	8333	P22077	Ethanone, 1-[5-[(2,4-difluorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,4-Difluorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone	-	CHEMSPIDER	28467528	C12H7F2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RMAMGGNACJHXHO-UHFFFAOYSA-N
28468	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Zhou B (2013)	23696216	211384	8391	AC17	1H-Indole-2-sulfonic acid, 5-[2-(aminocarbonyl)hydrazinylidene]-2,3,5,6-tetrahydro-1-methyl-6-oxo-, sodium salt (1:1)|Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate	-	CHEMSPIDER	21161414	C10H11N4NaO5S	small molecule	-	51460-26-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HLFCZZKCHVSOAP-UHFFFAOYSA-M
28469	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Zhou B (2013)	23696216	211384	8391	AC17	1H-Indole-2-sulfonic acid, 5-[2-(aminocarbonyl)hydrazinylidene]-2,3,5,6-tetrahydro-1-methyl-6-oxo-, sodium salt (1:1)|Sodium 5-(carbamoylhydrazono)-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonate	-	CHEMSPIDER	21161414	C10H11N4NaO5S	small molecule	-	51460-26-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HLFCZZKCHVSOAP-UHFFFAOYSA-M
28472	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28475	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Cao MN (2014)	24534329	211376	8392	Curcusone D	Benz[e]azulene-1,4-dione, 2,3,6a,7,8,9,10,10a-octahydro-2-hydroxy-2,5-dimethyl-10-methylene-7-(1-methylethenyl)-, (2R,6aS)-|(2R,6aS)-2-Hydroxy-7-isopropenyl-2,5-dimethyl-10-methylene-2,3,6a,7,8,9,10,10a-octahydrobenzo[e]azulene-1,4-dione	-	CHEMSPIDER	153282	C20H24O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DBPPEQIYWCILTJ-QUWZQRFGSA-N
28490	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24912524	211415	8578	CuPT	Copper(2+) bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, copper(2+) salt (2:1)	-	CHEMSPIDER	76402	C10H8CuN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XDUPUJNNHFTMQS-UHFFFAOYSA-N
28491	119509	51377	RP11-101E13.2	UCHL5	CGI-70|INO80R|UCH-L5|UCH37	9606	Homo sapiens	inhibitor	target	Liu N (2014)	24912524	211415	8578	CuPT	Copper(2+) bis(2-thioxo-1(2H)-pyridinolate)|2(1H)-Pyridinethione, 1-hydroxy-, copper(2+) salt (2:1)	-	CHEMSPIDER	76402	C10H8CuN2O2S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	XDUPUJNNHFTMQS-UHFFFAOYSA-N
28495	119489	51343	-	FZR1	CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1	9606	Homo sapiens	inhibitor	target	Zeng X (2010)	20951947	139860	8463	TAMe	TAME|tosyl-arginine methyl ester|tosyl-L-arginine methyl ester|Ts-Arg-OMe|p-toluensulfonyl-L-arginine methyl ester|Nalpha-p-tosyl-L-arginine methyl ester|methyl N2-(p-tosyl)-L-argininate|methyl N2-(p-toluenenesulfonyl)-L-argininate|methyl N2-[(p-tolyl)sulphonyl]-L-argininate|N2-(p-tolylsulfonyl)-L-arginine methyl ester|methyl N2-[(4-methylphenyl)sulfonyl]-L-argininate	-	CHEBI	62167	C14H22N4O4S	small molecule	-	1784-03-08	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	FKMJXALNHKIDOD-LBPRGKRZSA-N
28496	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Lamberto I (2017)	29056421	211372	8464	9QD	XL188|N-[3-[[4-Hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-4-oxoquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide|N-[3-({4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl}methyl)-4-oxo-3,4-dihydroquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide|SCHEMBL20856972|(R)-N-(3-((4-Hydroxy-1-(3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)-3-(4-methylpiperazin-1-yl)propanamide|2305045-76-3	-	PDB	9QD	C32H42N6O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QLBYDWATOPNXBG-XMMPIXPASA-N
28511	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Gavory G (2018)	29200206	213952	8576	3-[4-(Aminomethyl)phenyl]-6-{[4-hydroxy-1-(4,4,4-trifluoro-3-phenylbutanoyl)-4-piperidinyl]methyl}-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one	7H-Pyrazolo[4,3-d]pyrimidin-7-one, 3-[4-(aminomethyl)phenyl]-2,6-dihydro-6-[[4-hydroxy-1-(4,4,4-trifluoro-1-oxo-3-phenylbutyl)-4-piperidinyl]methyl]-2-methyl-|3-[4-(Aminomethyl)phenyl]-6-{[4-hydroxy-1-(4,4,4-trifluoro-3-phenylbutanoyl)-4-piperidinyl]methyl}-2-methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one	-	CHEMSPIDER	65324406	C29H31F3N6O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	PDB ID 5N9T	RLPQYKGBXQQARM-UHFFFAOYSA-N
28512	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Gavory G (2018)	29200206	213952	8575	7-bromanyl-3-[[4-oxidanyl-1-[(3~{R})-3-phenylbutanoyl]piperidin-4-yl]methyl]thieno[3,2-d]pyrimidin-4-one	7-Bromo-3-{[4-hydroxy-1-(3-phenylbutanoyl)-4-piperidinyl]methyl}thieno[3,2-d]pyrimidin-4(3H)-one|Thieno[3,2-d]pyrimidin-4(3H)-one, 7-bromo-3-[[4-hydroxy-1-(1-oxo-3-phenylbutyl)-4-piperidinyl]methyl]-	-	CHEMSPIDER	65324407	C22H24BrN3O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	PDB ID 5N9R	NRRXSEFLOFZNSO-UHFFFAOYSA-N
28528	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor	target	Sun B (2018)	28663582	210027	8577	birabresib	OTX015|(S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide|MFCD26960949|birabresib|MK-8628|X40LKS49S3|10407|2-[(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)acetamide|6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6S)-|OTX-015	-	CHEMSPIDER	8112374	C25H22ClN5O2S	small molecule	-	202590-98-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GNMUEVRJHCWKTO-FQEVSTJZSA-N
28532	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2011)	21343295	220329	8618	MNS	MNS|3,4-Methylenedioxy-.beta.-nitrostyrene|3,4-Methylenedioxy-beta-nitrostyrene|1,3-Benzodioxole, 5- (2-nitroethenyl)-|5-[(E)-2-Nitrovinyl]-1,3-benzodioxole|1,3-Benzodioxole, 5-[(E)-2-nitroethenyl]-|Syk Inhibitor III|MFCD00014575|WL5270000|5-(2-NITRO-VINYL)-BENZO(1,3)DIOXOLE	-	CHEMSPIDER	585303	C9H7NO4	small molecule	-	1485-00-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KFLWBZPSJQPRDD-ONEGZZNKSA-N
28533	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2011)	21383145	220330	8574	DBeQ	2,4-dibenzylaminoquinazoline|2,4-Quinazolinediamine, N~2~,N~4~-bis(phenylmethyl)-|DBeQ|N2,N4-dibenzylquinazoline-2,4-diamine|N,N'-Dibenzyl-2,4-quinazolinediamine|MFCD03691820|JRF 12	-	CHEMSPIDER	589082	C22H20N4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QAIMUUJJAJBPCL-UHFFFAOYSA-N
28534	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Magnaghi P (2013)	23892893	220331	8581	NMS-873	Pyridine, 3-[3-(cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-|NMS-873|MFCD28009371|3-[3-Cyclopentylsulfanyl-5-(4'-methanesulfonyl-2-methylbiphenyl-4-yloxymethyl)-[1,2,4]triazol-4-yl]-pyridine|3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-pyridine|3-[3-(Cyclopentylsulfanyl)-5-({[2-methyl-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-4H-1,2,4-triazol-4-yl]pyridine	-	CHEMSPIDER	29398603	C27H28N4O3S2	small molecule	-	1418013-75-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UJGTUKMAJVCBIS-UHFFFAOYSA-N
28537	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Wrigley JD (2017)	29131570	207318	8579	AZ1	Ethanol, 2-[[[5-bromo-2-[[4-fluoro-3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]amino]-|2-[(5-Bromo-2-{[4-fluoro-3-(trifluoromethyl)benzyl]oxy}benzyl)amino]ethanol	-	CHEMSPIDER	78316098	C17H16BrF4NO2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ITHSFXDGKQYOED-UHFFFAOYSA-N
28545	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8594	BI8622	N-[4-(Aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-4-pyrimidinecarboxamide|4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-	-	CHEMSPIDER	75533993	C25H26N6O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IJHAXMJRQQTBPL-UHFFFAOYSA-N
28546	115385	10075	RP3-339A18.4	HUWE1	ARF-BP1|HECTH9|HSPC272|Ib772|LASU1|MULE|URE-B1|UREB1	9606	Homo sapiens	inhibitor	target	Peter S (2014)	25253726	223665	8617	BI8626	1,3-Benzenedimethanamine, N~1~-[8-[4-(phenylmethyl)-1-piperazinyl]pyrimido[5,4-d]pyrimidin-4-yl]-|N-[3-(Aminomethyl)benzyl]-8-(4-benzyl-1-piperazinyl)pyrimido[5,4-d]pyrimidin-4-amine	-	CHEMSPIDER	75533990	C25H28N8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DZDNGSNKWIORRZ-UHFFFAOYSA-N
28547	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Senisterra G (2018)	29562800	213633	8584	NV03	Thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide, N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-|N-[3-(Diethylamino)propyl]-2-(5,9-dimethyl-8-oxothieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazin-7(8H)-yl)acetamide	-	CHEMSPIDER	78316460	C19H27N5O2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	NV03 is an antagonist of the UHRF1 - H3K9me3 interaction	KNZQAVKYBBYDKV-UHFFFAOYSA-N
28548	113168	7320	-	UBE2B	E2-17kDa|HHR6B|HR6B|RAD6B|UBC2	9606	Homo sapiens	inhibitor	target	Sanders MA (2013)	23339190	150227	8622	TZ9	1,3,5-Triazine-2-methanol, 4-amino-6-(phenylamino)-, 4-nitrobenzoate (ester)|(4-Amino-6-anilino-1,3,5-triazin-2-yl)methyl 4-nitrobenzoate	-	CHEMSPIDER	5909766	C17H14N6O4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RRRDZFQRNJTKHL-UHFFFAOYSA-N
28553	114554	9100	-	USP10	UBPO	9606	Homo sapiens	inhibitor	target	Shao S (2014)	24585095	223668	8614	Spautin-1	MFCD16962292|4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-|6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine|6-fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine|Spautin-1|C43	-	CHEMSPIDER	25199963	C15H11F2N3	small molecule	-	1262888-28-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	AWIVHRPYFSSVOG-UHFFFAOYSA-N
28557	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Colombo M (2010)	20186914	223669	8593	DUBs-IN-1	DUBs-IN-1|(9E)-9-[(Benzyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile|9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]-, (9E)-	-	CHEMSPIDER	17225091	C20H11N5O	small molecule	-	924296-18-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GKOWDIBLCDZJHF-NCELDCMTSA-N
28559	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28560	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8332	P50429	USP7/USP47 inhibitor|4-Cyano-5-[(3,5-dichloro-4-pyridinyl)sulfanyl]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide|2-Thiophenecarboxamide, 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-	-	CHEMSPIDER	28668733	C18H11Cl2N3O3S3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GUDJFFQZIISQJB-UHFFFAOYSA-N
28562	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Kategaya L (2017)	29045385	208946	8608	GNE-6640	4-[2-Amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]phenol|Phenol, 4-[2-amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridinyl]-	-	CHEMSPIDER	61716303	C20H18N4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZHYXJQQBKROZDX-UHFFFAOYSA-N
28563	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Kategaya L (2017)	29045385	208946	8609	GNE-6776	[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-|6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-3,3'-bipyridine-6-carboxamide	-	CHEMSPIDER	61716302	C20H20N4O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	UCYSSYGGXOFJKK-UHFFFAOYSA-N
28564	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Turnbull AP (2017)	29045389	220338	8607	FT671	4H-Pyrazolo[3,4-d]pyrimidin-4-one, 5-[[1-[(3S)-4,4-difluoro-3-(3-fluoro-1H-pyrazol-1-yl)-1-oxobutyl]-4-hydroxy-4-piperidinyl]methyl]-1-(4-fluorophenyl)-1,5-dihydro-|5-({1-[(3S)-4,4-Difluoro-3-(3-fluoro-1H-pyrazol-1-yl)butanoyl]-4-hydroxy-4-piperidinyl}methyl)-1-(4-fluorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one	-	CHEMSPIDER	61709033	C24H23F4N7O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	BLSNYSFLZAWBIV-SFHVURJKSA-N
28565	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Ritorto MS (2014)	25159004	223671	8344	BAY 11-7082	3-(p-Tolylsulfonyl)acrylonitrile|3-(p-Toluenesulfonyl)acrylonitrile|3-((4-Methylphenyl)sulfonyl)-2-propenenitrile|2-Propenenitrile, 3-((4-methylphenyl)sulfonyl)-|(E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile|BAY 11-7082|(2E)-3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile|2-Propenenitrile, 3-[(4-methylphenyl)sulfonyl]-, (2E)-|(2E)-3-[(4-Methylphenyl)sulfonyl]acrylonitrile|(E)-3-(P-TOLUENESULFONYL)ACRYLONITRILE	-	CHEMSPIDER	4510086	C10H9NO2S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOEWDSDBFRHVAP-KRXBUXKQSA-N
28573	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang Y (2018)	30254335	212629	8589	IU1-248	Benzonitrile, 4-[3-[2-(4-hydroxy-1-piperidinyl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]-|4-{3-[(4-Hydroxy-1-piperidinyl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzonitrile	-	CHEMSPIDER	88296270	C20H23N3O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	WFOUOZGIXDMUJU-UHFFFAOYSA-N
28574	114551	9097	-	USP14	TGT	9606	Homo sapiens	inhibitor	target	Wang Y (2018)	30254335	212629	8587	IU1-206	Ethanone, 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxy-1-piperidinyl)-|1-[1-(4-Chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(4-hydroxy-1-piperidinyl)ethanone	-	CHEMSPIDER	30575231	C19H23ClN2O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ORYIJHQLVLSPRM-UHFFFAOYSA-N
28577	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhou B (2018)	28339196	211345	8466	Bivalent ligand 39	BETd-260|Bivalent_ligand_39	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BETd-260(CRBN:thalidomide --- BDR4:HJB97 (compound 8))	-
28587	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Testa A (2018)	29949369	213521	8431	Bivalent ligand 65	Bivalent_ligand_65|PROTAC 15a	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 15a (VHL: F-Hyp-containing HIF-1 epitope peptide --- BRD4:JQ1)	-
28591	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Qin C (2018)	30019901	215015	8497	Bivalent ligand 67	QCA570|Bivalent_ligand_67	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: QCA570 (CRBN:thalidomide --- BDR4: QCA276 (BET inhibitor 22))	-
28611	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Bian J (2018)	30196207	214922	8515	Bivalent ligand 77	compund 11c|Bivalent_ligand_77	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	11c|Standardized BVL Name: (CRBN:pomalidomide ---CDK9:wogonin)	-
28615	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	DeMars KM (2019)	30872008	215612	8445	Bivalent ligand 15	Bivalent_ligand_15|dBET1|dBET6	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dBET1(CRBN:thalidomide --- BRD4:JQ1)	-
28617	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hines J (2019)	30385614	215621	8518	Bivalent ligand 78	A1874|Bivalent_ligand_78	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: A1874(MDM2:idasanutlin --- BRD4:JQ1)	-
28623	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Olson CM (2018)	29251720	214651	8491	Bivalent ligand 83	THAL-SNS-032|Bivalent_ligand_83	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS-032 (CRBN: thalidomide --- CDK9:SNS-032)	-
28647	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhang X (2019)	31209349	220534	8544	Bivalent ligand 92	KB02-JQ1|Bivalent_ligand_92	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	small molecule|Standardized BVL Name: KB02-JQ1 (DCAF16:KB02 --- BRD4:JQ1)	-
28659	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Zhao Q (2019)	31539241	220727	8502	Bivalent ligand 97	SIAIS178|Bivalent_ligand_97	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS178 (VHL:VHL1 --- BCR-ABL:dasatinib)	-
28663	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Burslem GM (2019)	31311809	223347	8506	Bivalent ligand 100	GMB-475|Bivalent_ligand_100	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: GMB-475(VHL:VHL1 --- BCR-ABL1:GNF-5)	-
28677	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chan KH (2018)	28595007	223620	8539	Bivalent ligand 106	MZP-54|MZP-55|Bivalent_ligand_106	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MZP-55 (VHL: --- BRD4:I-BET726)	-
28679	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chan KH (2018)	28595007	223620	8408	Bivalent ligand 45	Bivalent_ligand_45|ARV-825	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ARV-825(CRBN:pomalidomide --- BRD4:OTX015)	-
28681	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chan KH (2018)	28595007	223620	8407	Bivalent ligand 44	Bivalent_ligand_44|compound MZ1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound MZ1(VHL:VHL-1 --- BRD4:JQ1)	-
28683	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Zhao Q (2019)	30540295	223621	8505	Bivalent ligand 107	compound-3|Bivalent_ligand_107	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	110358	4193	-	MDM2	ACTFS|HDMX|hdm2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound-3 (MDM2:nutlin-3 --- PARP1:niraparib)	-
28687	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Zhang F (2020)	31813613	223623	8500	Bivalent ligand 109	compound 21|Bivalent_ligand_109	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 21 (CRBN:pomalidomide --- BRD4:compound 5)	-
28741	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK7:TL13-87)	-
28751	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
28753	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Huang HT (2018)	29129717	211728	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK9:TL13-87)	-
28777	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Qiu X (2019)	31066567	223631	8533	Bivalent ligand 124	SIAIS213110|Bivalent_ligand_124	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS213110 (CRBN:lenalidomide --- BRD4:JQ1-acid)	-
28779	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Lebraud H (2016)	28058282	223632	8534	Bivalent ligand 125	JQ1-CLIPTAC|Bivalent_ligand_125	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	CLIPTAC	PROTAC variant formed in cells by click chemistry; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: JQ1-CLIPTAC (CRBN:Tz-thalidomide --- BRD4:JQ1)	-
28847	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Mu X (2020)	31708096	223603	8559	Bivalent ligand 141	HBL-4|Bivalent_ligand_141	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HBL-4  (CRBN:thalidomide --- BRD4:BI2536)	-
28893	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Li L (2020)	32713946	223646	8564	Bivalent ligand 146	DP1|Bivalent_ligand_146	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	124705	90379	-	DCAF15	C19orf72	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DP1(DCAF15:E7820 --- BRD4:JQ1)	-
28917	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Tong B (2020)	32568522	223653	8547	Bivalent ligand 153	BT1|Bivalent_ligand_153	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BT1 (RNF114:nimbolide --- BCR-ABL:dasatinib)	-
28921	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Burslem GM (2020)	32519703	223655	8553	Bivalent ligand 155	GMB-805|Bivalent_ligand_155	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: GMB-805 (VHL:VHL1 --- BCR-ABL:ABL001)	-
28931	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ward CC (2019)	31059647	220118	8477	Bivalent ligand 160	CCW 28-3|Bivalent_ligand_160	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	111974	6047	RES4-26	RNF4	SLX5|SNURF	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CCW 28-3 (RNF4:CCW 16 --- BRD4:JQ1)	-
28933	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Spradlin JN (2019)	31209351	220371	8478	Bivalent ligand 161	XH2|Bivalent_ligand_161	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	120991	55905	-	RNF114	PSORS12|ZNF313	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: XH2 (RNF114:nimbolide --- BRD4:JQ1)	-
28949	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Jiang B (2019)	30802347	223660	8482	Bivalent ligand 165	BSJ-01-184|Bivalent_ligand_165	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ01184 (CRBN:thalidomide --- CDK9:abemaciclib)	-
29274	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	9308	Midostaurin	CCG-101288|SB16639|HY-10230|HMS3229K17|CGP 41 251|ZINC100013130|MIDOSTAURIN(PKC412)|PKC 412|CGP 41251|N-[(2S,3R,4R,6R)-3-METHOXY-2-METHYL-16-OXO-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-4-YL]-N-METHYLBENZAMIDE|RYDAPT (TN)|PKC412|[9S-(9?,10?,11?,13?)]-N-(2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-1-OXO-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-11-YL)-N-METHYLBENZAMIDE|ACN-036840|4'-N-BENZOYLSTAUROSPORINE|BENZOYLSTAUROSPORINE|CGP-41251|MIDOSTAURIN [USAN:INN]|EX-A1741|N-BENZOYLSTAUROSPORINE|120685-11-2|D05029|CGP 41231|Q6842945|BRD-K13646352-001-01-2|DB06595|MIDOSTAURIN (JAN/USAN/INN)|CS-3331|NCGC00484987-03|Z-3116|N-[(5S,6R,7R,9R)-6-METHOXY-5-METHYL-14-OXO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-7-YL]-N-METHYLBENZAMIDE|CGP-41521|ID912S5VON|AKOS024457372|PKC-412|UNII-ID912S5VON|NCGC00241102-02|GTPL5702|NVP-PKC412|J-004379|RYDAPT|MIDOSTAURIN|S8064|NCGC00241102-01|BDBM50326053	-	PUBCHEM	9829523	C35H30N4O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	BMGQWWVMWDBQGC-IIFHNQTCSA-N
29275	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Karaman MW (2008)	18183025	224791	1934	Staurosporine	2GCD|BCPP000063|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-METHYLAMINO-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-09|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- (9CI)|ANTIBIOTIC AM-2282|EX-A1777|9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)-BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S-(9ALPHA,10BETA,11BETA,13ALPHA)-|HMS3650B17|NCGC00162400-06|H88EPA0A3N|8-METHOXY-9-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-16-OL|BRD-K17953061-001-02-8|62996-74-1|BRD-K17953061-001-11-9|109189-95-9|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8,10,12,14(28),15(19),20(27),21,23,25-NONAEN-16-ONE|1U59|CCG-208052|STAUROSPORINE & TUMOR NECROSIS FACTOR (TNF)|NCGC00162400-02|2DQ7|MEGXM0_000307|1NVR|STAUROSPORINE;9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)-|BRD-K17953061-001-05-1|NCGC00162400-03|7158-EP2289893A1|8,12-EPOXY-1H,8H-2,7B,12A-TRIAZADIBENZO(A,G)CYCLONONA(CDE)TRINDEN-1-ONE, 2,3,9,10,11,12-HEXAHYDRO-9-METHOXY-8-METHYL-10-(METHYLAMINO)-, (8ALPHA,9BETA,10BETA,12ALPHA)-(+)-|CGP 39360|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]NONACOSA-8(13),9,11,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|AM-2282|ANTIBIOTIC AM 2282|1XJD|STAUROSPORIN|STAUROSPORINE & TNF|7158-EP2311842A2|STAUROSPORIN, 4|DB02010|METHOXY-METHYL-(METHYLAMINO)[?]ONE|NCGC00162400-01|GNF-PF-1389|7158-EP2292617A1|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, [9S-(9ALPHA,10BETA,11BETA,13ALPHA)]-|ANTIBIOTIC 230|7158-EP2308855A1|ALKALOID AM-2282 FROM STREPTOMYCES|ST50826371|1STC|HY-15141|MOLMAP_000047|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|NCGC00162400-04|(+)-STAUROSPORINE|GTPL346|7158-EP2311809A1|Q5957181|CS-2716|STAUROSPORINE, 8|AKOS015897119|BIO1_000753|BRD-K17953061-001-04-4|SR-00000001485-4|STAUROSPORINE|7158-EP2308883A1|BRD-K17953061-001-10-1|NCGC00162400-05|[9S-(9?,10?,11?,13?)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE|LS-64042|CBIOL_001978|1SM2|1Q3D|BIO1_000264|1YHS|ZINC3814434|S1421|SR-00000001485|UNII-H88EPA0A3N|7158-EP2270008A1|(5S,6R,7R,9R)-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9,15,16-HEXAHYDRO-5H,14H-17-OXA-4B,9A,15-TRIAZA-5,9-METHANODIBENZO[B,H]CYCLONONA[JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE|9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE, 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-, (9S,10R,11R,13R)- & TUMOR NECROSIS FACTOR (TNF)|(2S,3R,4R,6R)-3-METHOXY-2-METHYL-4-(METHYLAMINO)-29-OXA-1,7,17-TRIAZAOCTACYCLO [12.12.2.1<2,6>.0<7,28>.0<8,13>.0<15,19>.0<20,27>.0<21,26>]NONACOSA-8(13),9,11 ,14(28),15(19),20(27),21(26),22,24-NONAEN-16-ONE|QTL1_000078|HMS1990J07|BIO1_001242|1XBC|DTXSID30911019|CCRIS 3272|BSPBIO_001146|BRD-K17953061-001-08-5|BDBM2579	-	DRUGBANK	DB02010	C28H26N4O3	small molecule	-	62996-74-1	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	HKSZLNNOFSGOKW-UCBFMKAXSA-N
29335	124084	84446	-	BRSK1	hSAD1	9606	Homo sapiens	unknown	target	Simov V (2016)	26927423	224809	9342	BDBM50152595	-	-	CHEMBL	CHEMBL3780091	C18H21N5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	JLWGOAGEDWMEBT-TXEJJXNPSA-N
29361	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Alverez C (2015)	26713109	224816	9366	1-[3-(5-Nitro-1H-indol-2-yl)phenyl]-N-[2-(4-propan-2-ylpiperazin-1-yl)ethyl]piperidin-4-amine	J3.640.579A|C(C)(C)N1CCN(CC1)CCNC1CCN(CC1)C1=CC(=CC=C1)C=1NC2=CC=C(C=C2C=1)[N+](=O)[O-]|N-[2-(4-ISOPROPYLPIPERAZINO)ETHYL]-1-[3-(5-NITRO-1H-INDOLE-2-YL)PHENYL]PIPERIDINE-4-AMINE|BDBM50158905	-	PUBCHEM	127031857	C28H38N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QOGCSASIXKSUDD-UHFFFAOYSA-N
29524	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9500	BDBM50040557	-	-	CHEMBL	CHEMBL3361178	C24H25N5O4	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	RFOKLKNGIPKNDF-JCNLHEQBSA-N
29525	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9501	BDBM50040551	-	-	CHEMBL	CHEMBL3361184	C25H28N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	UVMHVBWGXWQOLU-XUTJKUGGSA-N
29526	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9502	BDBM50040550	-	-	CHEMBL	CHEMBL3361185	C24H26N4O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	FPPFUGYLWPKNTA-UAPYVXQJSA-N
29527	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9503	BDBM50040513	-	-	CHEMBL	CHEMBL3361210	C25H28FN5O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	VLNGECBZQIDCNU-WGSAOQKQSA-N
29528	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9504	BDBM50040512	-	-	CHEMBL	CHEMBL3361211	C27H31N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMCROPORCNMTHB-MEMLXQNLSA-N
29529	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9505	BDBM50040506	-	-	CHEMBL	CHEMBL3361216	C27H32N6O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	QYDMQKBOHABCOZ-AQYVVDRMSA-N
29530	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9506	BDBM50040505	-	-	CHEMBL	CHEMBL3361217	C26H31N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	IAHVLWVJZMFEPN-XYWHTSSQSA-N
29531	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9507	BDBM50040499	-	-	CHEMBL	CHEMBL3361223	C27H29N5O2	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LMBRNCPCPMAUCV-MXVIHJGJSA-N
29532	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9508	BDBM50040498	-	-	CHEMBL	CHEMBL3361224	C26H29N7O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	XBDONALUAKOWDJ-WGSAOQKQSA-N
29533	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9509	BDBM50040497	-	-	CHEMBL	CHEMBL3361225	C27H29N5OS	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	PUERLUHEKCOMSQ-MXVIHJGJSA-N
29534	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	unknown	target	Cervi G (2014)	25474526	171150	9510	BDBM50040496	-	-	CHEMBL	CHEMBL3361226	C27H30N6O	small molecule	-	-	BINDINGDB	-	-	-	-	-	-	-	-	-	-	-	LJIJDHSXMUSZQW-MXVIHJGJSA-N
29842	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Tang WK (2019)	30591537	219833	9881	CB-5083	1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide|1H-Indole-4-carboxamide, 1-[7,8-dihydro-4-[(phenylmethyl)amino]-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-|CB-5083|591IV6UL6J	-	CHEMSPIDER	35519806	C24H23N5O2	small molecule	-	1542705-92-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	RDALZZCKQFLGJP-UHFFFAOYSA-N
29843	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2013)	23316025	228646	9895	ML240	2-(2-Amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxy-4-quinazolinamine|ML240|CID-49830258|MFCD28137687|ML-240|2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine|4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-	-	CHEMSPIDER	34500429	C23H20N6O	small molecule	-	1346527-98-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NHAMBLRUUJAFOY-UHFFFAOYSA-N
29844	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Chou TF (2013)	23316025	228646	9927	ML241	N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine hydrochloride (1:1)|4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)-, hydrochloride (1:1)	-	CHEMSPIDER	57251285	C23H25ClN4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DYHMHNNBOLCULH-UHFFFAOYSA-N
29845	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Poehler R (2018)	29271116	216019	9861	MSC1094308	4,4-Bis(4-fluorophenyl)-N-[(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methyl]-1-butanamine|1H-Carbazole-3-methanamine, N-[4,4-bis(4-fluorophenyl)butyl]-6-fluoro-2,3,4,9-tetrahydro-	-	CHEMSPIDER	78316408	C29H29F3N2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	OCZIMUMAPGQEBH-UHFFFAOYSA-N
29846	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Magnaghi P (2013)	23892893	220331	9840	NMS-859	Acetamide, 2-chloro-N-[3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl]-|2-Chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]phenyl}acetamide	-	CHEMSPIDER	34224308	C15H12ClN3O3S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JWMFLBAPPIWNGG-UHFFFAOYSA-N
29847	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Sasazawa Y (2012)	22360440	228647	9900	Xanthohumol	2-propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-|Xanthohumol|(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one|MFCD00210576|2',4,4'-trihydroxy-6'-methoxy-3'-prenylchalcone|1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one|T4467YT1NT|(E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)propenone|(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one|XANTHOHUMOL FROM HOP (HUMULUS LUPULUS)|2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-	-	CHEMSPIDER	555077	C21H22O5	small molecule	-	569-83-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ORXQGKIUCDPEAJ-YRNVUSSQSA-N
29931	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Ndubaku C (2015)	25364867	228674	9922	2-phenylbenzo[f][1,3]benzoxazole-4,9-dione	-	-	CHEMSPIDER	444479	C17H9NO3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CMYQQADDUUDCCA-UHFFFAOYSA-N
29937	113041	7189	-	TRAF6	MGC:3310|RNF85	9606	Homo sapiens	inhibitor	target	Brenke JK (2018)	29950522	216477	9880	C25-140	1-Propanone, 3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-|1-(4-Benzyl-1-piperidinyl)-3-[3,5-dimethyl-1-(3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-propanone	-	CHEMSPIDER	29053655	C26H31N7O	small molecule	-	1358099-18-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	HFKVRXVHZGBRKF-UHFFFAOYSA-N
29938	118893	29128	-	UHRF1	ICBP90|Np95|RNF106|hNP95|hUHRF1|huNp95	9606	Homo sapiens	inhibitor	target	Myrianthopoulos V (2016)	27049577	195311	9904	NSC232003	(5Z)-5-[1-(Hydroxyamino)ethylidene]-2,4(3H,5H)-pyrimidinedione|2,4(3H,5H)-Pyrimidinedione, 5-[1-(hydroxyamino)ethylidene]-, (5Z)-	-	CHEMSPIDER	4513358	C6H7N3O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	IXSSYZRLNVZFMP-ARJAWSKDSA-N
29961	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9895	ML240	2-(2-Amino-1H-benzimidazol-1-yl)-N-benzyl-8-methoxy-4-quinazolinamine|ML240|CID-49830258|MFCD28137687|ML-240|2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine|4-Quinazolinamine, 2-(2-amino-1H-benzimidazol-1-yl)-8-methoxy-N-(phenylmethyl)-	-	CHEMSPIDER	34500429	C23H20N6O	small molecule	-	1346527-98-7	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NHAMBLRUUJAFOY-UHFFFAOYSA-N
29962	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9887	LC-1028	N-{1-[(4Z)-4-(Benzylimino)-3,4,5,6,7,8-hexahydro-2-quinazolinyl]-2-methyl-1H-indol-4-yl}-2-butynamide|2-Butynamide, N-[1-[(4Z)-3,4,5,6,7,8-hexahydro-4-[(phenylmethyl)imino]-2-quinazolinyl]-2-methyl-1H-indol-4-yl]-	-	CHEMSPIDER	88296358	C28H27N5O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	YOUVOKAIDVNCJA-UHFFFAOYSA-N
29963	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9854	UPCDC30245	1-[3-(5-Fluoro-1H-indol-2-yl)phenyl]-N-[2-(4-isopropyl-1-piperazinyl)ethyl]-4-piperidinamine|1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)-|1-(3-(5-Fluoro-1h-Indol-2-Yl)phenyl)piperidin-4-Yl)(2-(4-Isopropyl-Piperazin1-Yl)ethyl)-Carbamate|1-(3-(5-Fluoro-1H-indol-2-yl)phenyl)-N-(2-(4-isopropylpiperazin-1-yl)ethyl)piperidin-4-amine|UPCDC30245	-	CHEMSPIDER	58825106	C28H38FN5	small molecule	-	1883351-01-6	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LZHXZCVDLATFAR-UHFFFAOYSA-N
29964	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Alverez C (2016)	26985295	195724	9879	SMDC818909	3-Amino-N-(2-methyl-1H-indol-5-yl)-2-pyrazinecarboxamide|2-Pyrazinecarboxamide, 3-amino-N-(2-methyl-1H-indol-5-yl)-	-	CHEMSPIDER	30141951	C14H13N5O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	PJTNJJWGQNSQDQ-UHFFFAOYSA-N
29965	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Alverez C (2016)	26985295	195724	9849	2-Amino-N-(2-methyl-1H-indol-5-yl)nicotinamide	3-Pyridinecarboxamide, 2-amino-N-(2-methyl-1H-indol-5-yl)-|2-Amino-N-(2-methyl-1H-indol-5-yl)nicotinamide	-	CHEMSPIDER	75831997	C15H14N4O	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GWHPATATCVJNBI-UHFFFAOYSA-N
29966	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Huryn DM (2020)	31550150	228641	9932	Eeyarestatin 1	Eeyarestatin I|3-(4-Chlorophenyl)-1-[3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitro-2-furyl)prop-2-en-1-ylidene]hydrazino}-2-oxoethyl)-2-oxoimidazolidin-4-yl]-1-hydroxyurea|1-Imidazolidineacetic acid, 3-(4-chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-, 2-[(1E,2E)-3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide|3-(4-Chlorophenyl)-1-[3-(4-chlorophenyl)-5,5-dimethyl-1-(2-{(2E)-2-[(2E)-3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazino}-2-oxoethyl)-2-oxo-4-imidazolidinyl]-1-hydroxyurea|Eeyarestatin 1	-	CHEMSPIDER	24606066	C27H25Cl2N7O7	small molecule	-	412960-54-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	JTUXTPWYZXWOIB-LWWHHIEBSA-N
29967	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	250	Clotrimazole	Mycelex (tn)|1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole|Clotrimazole|1-(o-Chlorotrityl)imidazole|Lotrimin (tn)|1-(-(2-Chlorophenyl)benzhydryl)imidazole|1-(o-Chloro-,-diphenylbenzyl)imidazole|1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole|1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole	myclo solution|clotrimazole ex	DRUGBANK	DB00257	C22H17ClN2	small molecule	A01AB18|G01AF02|D01AC01	23593-75-1	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	VNFPBHJOKIVQEB-UHFFFAOYSA-N
29968	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	627	Astemizole	Astemizolum|1-(P-Fluorobenzyl)-2-((1-(P-methoxyphenethyl)-4-piperidyl)amino)benzimidazole|1-(P-Fluorobenzyl)-2-((1-(2-(P-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole|Astemison|Astmizole|Astemizol	hismanal tab 10mg|hismanal sus	DRUGBANK	DB00637	C28H31FN4O	small molecule	R06AX11	68844-77-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GXDALQBWZGODGZ-UHFFFAOYSA-N
29969	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Segura-Cabrera A (2017)	28322292	228692	9907	Ebastine	Ebastine|1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone|4'-tert-Butyl-4-[4-(diphenylmethoxy)piperidino]butyrophenone|4-Diphenylmethoxy-1-[3-(4-tert-butylbenzoyl)propyl]piperidine|4-[4-(Diphenylmethoxy)-1-piperidinyl]-1-[4-(2-methyl-2-propanyl)phenyl]-1-butanone|1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-|1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one|Ebastin|MFCD00865661	-	CHEMSPIDER	3079	C32H39NO2	small molecule	-	90729-43-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	MJJALKDDGIKVBE-UHFFFAOYSA-N
29970	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Wijeratne EM (2016)	26812276	228693	9897	Oxaspirol B	2-Oxaspiro[4.5]dec-7-ene-1,4-dione, 6-[(1E,3E)-1,3-heptadien-1-yl]-9,10-dihydroxy-3-methylene-, (6R,9R,10R)-|(6R,9R,10R)-6-[(1E,3E)-1,3-Heptadien-1-yl]-9,10-dihydroxy-3-methylene-2-oxaspiro[4.5]dec-7-ene-1,4-dione	-	CHEMSPIDER	58927941	C17H20O5	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GIXMLHVPEUCNBI-VRRHEOGASA-N
29971	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor	target	Suvarna K (2019)	30610116	228694	9856	NPD8733	N-[2-(4-Methoxybenzoyl)-1-benzofuran-3-yl]acetamide|Acetamide, N-[2-(4-methoxybenzoyl)-3-benzofuranyl]-	-	CHEMSPIDER	792712	C18H15NO4	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	NQZBUYPGHZTWIR-UHFFFAOYSA-N
29973	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
29974	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Weinstock J (2012)	24900381	223670	8334	P5091	Ethanone, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-|1-{5-[(2,3-Dichlorophenyl)sulfanyl]-4-nitro-2-thienyl}ethanone|1-{5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl}ethan-1-one	-	CHEMSPIDER	2098223	C12H7Cl2NO3S2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	LKZLGMAAKNEGCH-UHFFFAOYSA-N
29976	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	821	Trifluoperazine	10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine|10-[3-(4-METHYL-piperazin-1-yl)-propyl]-2-trifluoromethyl-10H-phenothiazine|Trifluoroperazine|Trifluoperazinum|Trifluoperazina|Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine|Trifluperazine|Trifluoperazine	pms trifluoperazine hcl syrup 	DRUGBANK	DB00831	C21H24F3N3S	small molecule	N05AB06	117-89-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZEWQUBUPAILYHI-UHFFFAOYSA-N
29977	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Chen J (2011)	22118673	211359	821	Trifluoperazine	10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine|10-[3-(4-METHYL-piperazin-1-yl)-propyl]-2-trifluoromethyl-10H-phenothiazine|Trifluoroperazine|Trifluoperazinum|Trifluoperazina|Trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazine|Trifluperazine|Trifluoperazine	pms trifluoperazine hcl syrup 	DRUGBANK	DB00831	C21H24F3N3S	small molecule	N05AB06	117-89-5	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZEWQUBUPAILYHI-UHFFFAOYSA-N
29978	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9850	C527	c527|2-(4-Fluorophenyl)naphtho[2,3-d][1,3]oxazole-4,9-dione|Naphth[2,3-d]oxazole-4,9-dione, 2-(4-fluorophenyl)-	-	CHEMSPIDER	1725101	C17H8FNO3	small molecule	-	192718-06-2	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ULJDFEYQOPCCPM-UHFFFAOYSA-N
29983	113241	7398	-	USP1	UBP	9606	Homo sapiens	inhibitor	target	Mistry H (2013)	24130053	161617	9916	SJB3-019A	Naphth[2,3-d]oxazole-4,9-dione, 2-(3-pyridinyl)-|2-(3-Pyridinyl)naphtho[2,3-d][1,3]oxazole-4,9-dione	-	CHEMSPIDER	44208868	C16H8N2O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	DOYPPVCQHGJUBC-UHFFFAOYSA-N
29989	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Schauer NJ (2020)	31682427	228698	9906	NSC632839	4-Piperidinone, 3,5-bis[(4-methylphenyl)methylene]-, (3E)-, hydrochloride (1:1)|(3E)-3,5-Bis(4-methylbenzylidene)-4-piperidinone hydrochloride (1:1)	-	CHEMSPIDER	57427760	C21H22ClNO	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	ZOKZLTXPTLIWOJ-OJWWICQKSA-N
29990	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Schauer NJ (2020)	31682427	228698	9902	Spongiacidin A	Pyrrolo[2,3-c]azepin-8(1H)-one, 4-(2-amino-5-oxo-4-imidazolidinylidene)-2,3-dibromo-4,5,6,7-tetrahydro-, (4E)-|(4E)-4-(2-Amino-5-oxo-4-imidazolidinylidene)-2,3-dibromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8(1H)-one	-	CHEMSPIDER	24699820	C11H11Br2N5O2	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	CTHGIINQRBTFRV-ZZXKWVIFSA-N
29993	115301	9978	RP11-554C12.1	RBX1	BA554C12.1|RNF75|ROC1	9606	Homo sapiens	inhibitor	target	Yu Q (2020)	32145688	226735	9858	Gossypol	N,N,1,3-Tetramethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine|1H-Pyrazolo[3,4-d]pyrimidin-4-amine, N,N,1,3-tetramethyl-|Dipotassium Salt|Sodium Salt|BL193|ssypol|AT101|TASH1|POGOSIN	-	CHEMSPIDER	32145688	C30H30O8	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	QBKSWRVVCFFDOT-UHFFFAOYSA-N
30005	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Turnbull AP (2017)	29045389	220338	9882	FT827	Ethenesulfonamide, N-[4'-[[4-[(1,4-dihydro-1-methyl-4-oxo-5H-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-4-hydroxy-1-piperidinyl]carbonyl][1,1'-biphenyl]-2-yl]-|N-[4'-({4-Hydroxy-4-[(1-methyl-4-oxo-1,4-dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-yl)methyl]-1-piperidinyl}carbonyl)-2-biphenylyl]ethenesulfonamide	-	CHEMSPIDER	71117270	C27H28N6O5S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	GFNJQQBUZURQMA-UHFFFAOYSA-N
30009	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Zhang Z (2020)	32779949	228701	9770	Bivalent ligand 173	compound 2|Bivalent_ligand_173	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 2 (CRBN:lenalidomide --- PARP1: Olaparib)	-
30015	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Liu J (2020)	32128407	228702	9767	Bivalent ligand 174	opto-dBET1|Bivalent_ligand_174	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: opto-dBET1 (CRBN:opto-pomalidomide --- BRD4:JQ1)	-
30023	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2020)	32128406	228703	9769	Bivalent ligand 176	PHOTAC-I-3|Bivalent_ligand_176	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
30031	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Cao C (2020)	32924477	228706	9800	Bivalent ligand 180	SK-575|Bivalent_ligand_180	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-575 (CRBN:thalidomide --- PARP1: Olaparib)	-
30089	108474	2177	-	FANCD2	FA-D2|FA4|FACD|FAD|FAD2|FANCD	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8433	Bivalent ligand 63	Bivalent_ligand_63|PROTAC 1	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC1(VHL:VHL ligand --- FANCD2:foretinib)	-
30171	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9822	Bivalent ligand 216	dTAG-7|Bivalent_ligand_216	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-7 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30173	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Nabet B (2018)	29581585	228717	9823	Bivalent ligand 217	dTAG-13|Bivalent_ligand_217	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: dTAG-13 (CRBN:phthalimide --- BRD4-FKBP12F36V:AP1867)	-
30215	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9833	Bivalent ligand 219	iRucaparib-TP3|Bivalent_ligand_219	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-TP3 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30217	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9789	Bivalent ligand 220	iRucaparib-TP4|Bivalent_ligand_220	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-TP4 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30219	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9788	Bivalent ligand 221	vRucaparib-TP3|Bivalent_ligand_221	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: vRucaparib-TP3 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30221	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9791	Bivalent ligand 222	vRucaparib-TP4|Bivalent_ligand_222	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: vRucaparib-TP4 (VHL:HIF-1 peptide --- PARP1:Rucaparib)	-
30223	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9790	Bivalent ligand 223	iRucaparib-AP5|Bivalent_ligand_223	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-AP5 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30225	106652	142	RP11-125A15.2	PARP1	ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9793	Bivalent ligand 224	iRucaparib-AP6|Bivalent_ligand_224	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-AP6 (CRBN:pomalidomide --- PARP1:Rucaparib)	-
30227	115350	10038	-	PARP2	ADPRT2|ADPRTL2|ADPRTL3|ARTD2|PARP-2|pADPRT-2	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9792	Bivalent ligand 225	iVeliparib-AP6|Bivalent_ligand_225	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iVeliparib-AP6 (CRBN:pomalidomide --- PARP1:Veliparib)	-
30229	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9790	Bivalent ligand 223	iRucaparib-AP5|Bivalent_ligand_223	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-AP5 (CRBN:pomalidomide --- PARP3:Rucaparib)	-
30231	115351	10039	-	PARP3	ADPRT3|ADPRTL2|ADPRTL3|ARTD3|IRT1|PADPRT-3	9606	Homo sapiens	degradation	target	Wang S (2019)	31659317	228718	9793	Bivalent ligand 224	iRucaparib-AP6|Bivalent_ligand_224	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: iRucaparib-AP6 (CRBN:pomalidomide --- PARP3:Rucaparib)	-
30247	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Testa A (2020)	31746102	228721	9834	Bivalent ligand 230	macroPROTAC-1|Bivalent_ligand_230	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: macroPROTAC1 (VHL:VH032 ---BRD4:JQ1)	-
30264	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9804	Bivalent ligand 239	vhhGFP4-FBW7|Bivalent_ligand_239	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-FBW7 (FBW7:vhhGFP4 --- H2B:GFP)	-
30272	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9772	Bivalent ligand 243	vhhGFP4-CHIP|Bivalent_ligand_243	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113945	8349	-	HIST2H2BE	GL105|H2B|H2B.1|H2BFQ|H2BGL105|H2BQ	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-CHIP (CHIP:vhhGFP4 --- H2B:GFP)	-
30274	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9804	Bivalent ligand 239	vhhGFP4-FBW7|Bivalent_ligand_239	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-FBW7 (FBW7:vhhGFP4 --- PCNA:GFP)	-
30277	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9775	Bivalent ligand 240	vhhGFP4-VHL|Bivalent_ligand_240	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: vhhGFP4-VHL (VHL:vhhGFP4 --- PCNA:GFP)	-
30278	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2020)	32123106	226780	9772	Bivalent ligand 243	vhhGFP4-CHIP|Bivalent_ligand_243	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	target	Standardized BVL Name: vhhGFP4-CHIP (CHIP:vhhGFP4 --- PCNA:GFP)	-
30281	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9774	Bivalent ligand 241	vhhGFP4-SOCS2|Bivalent_ligand_241	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	114362	8835	-	SOCS2	CIS2|Cish2|SOCS-2|SSI-2|SSI2|STATI2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: vhhGFP4-SOCS2 (SOCS2:vhhGFP4 --- PCNA:GFP)	-
30283	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9813	Bivalent ligand 232	vhhGFP4-SPOP|Bivalent_ligand_232	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: vhhGFP4-SPOP (SPOP:vhhGFP4 --- PCNA-GFP)	-
30285	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9819	Bivalent ligand 233	3G86.32|Bivalent_ligand_233	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 3G86.32 (SPOP:3G86.32 --- PCNA:GFP)	-
30287	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9830	Bivalent ligand 234	bGFP-A|Bivalent_ligand_234	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: bGFP-A (SPOP:bGFP-A  --- PCNA:GFP)	-
30289	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9810	Bivalent ligand 235	bGFP-C|Bivalent_ligand_235	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: bGFP-C (SPOP:bGFP-C  --- PCNA:GFP)	-
30291	111142	5111	-	PCNA	ATLD2	9606	Homo sapiens	degradation	target	Lim S (2020)	32123106	226780	9828	Bivalent ligand 236	GS2|Bivalent_ligand_236	-	BIOGRID	-	-	polypeptidic	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase; NOTE: the format for this BVL name is (E3:GFP binding scaffold fusion --- Target:GFP fusion)	113993	8405	-	SPOP	BTBD32|TEF2	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: GS2 (SPOP:GS2 --- PCNA:GFP)	-
30308	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Lv L (2020)	32804079	223704	9760	Bivalent ligand 247	HQ461|Bivalent_ligand_247	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: HQ461 (DDB1:HQ461 --- CDK12 + CCNK:HQ461)	-
30310	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Slabicki M (2020)	32494016	228456	9807	Bivalent ligand 248	R-CR8|Bivalent_ligand_248	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: R-CR8 (DDB1:CR8 --- CDK12 + CCNK:CR8)	-
30312	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9764	Bivalent ligand 249	dCeMM1|Bivalent_ligand_249	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM1 (DDB1:dCeMM1 --- CDK12 + CCNK:dCeMM1)	-
30314	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9812	Bivalent ligand 250	dCeMM2|Bivalent_ligand_250	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM2 (DDB1:dCeMM2 --- CDK12 + CCNK:dCeMM2)	-
30316	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9759	Bivalent ligand 251	dCeMM3|Bivalent_ligand_251	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM3 (DDB1:dCeMM3 --- CDK12 + CCNK:dCeMM3)	-
30318	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Mayor-Ruiz C (2020)	32747809	228457	9814	Bivalent ligand 252	dCeMM4|Bivalent_ligand_252	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: dCeMM4 (DDB1:dCeMM4 --- CDK12 + CCNK:dCeMM4)	-
30329	108379	2067	-	ERCC1	COFS4|RAD10|UV20	9606	Homo sapiens	degradation	target	Bondeson DP (2018)	29129718	208144	8429	Bivalent ligand 64	Bivalent_ligand_64|PROTAC 2	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC2(CRBN:CRBN ligand --- ERCC1:foretinib)	-
30367	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Jin YH (2020)	32153174	223638	8521	Bivalent ligand 133	Azo-PROTAC-4C|Bivalent_ligand_133	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Azo-PROTAC-4C (CRBN:lenalidomide --- BCR-ABL:dasatinib)	-
30369	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Xue G (2019)	31566962	223639	8524	Bivalent ligand 134	pc-PROTAC1|Bivalent_ligand_134	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which degradation activity can be regulated by exposure to light; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pc-PROTAC1 (CRBN:thalidomide --- BCR4:JQ1)	-
30379	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Li X (2020)	32029476	227136	9970	Parthenolide	Parthenolide|(1aR,4E,7aS,10aS,10bR)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one|Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-1a,5-dimethyl-8-methylene-, (1aR,4E,7aS,10aS,10bR)-|(-)-Parthenolide|(1aR,4E,7aS,10aS,10bR)-1a,5-Dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one	-	CHEMSPIDER	4976071	C15H20O3	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	-	KTEXNACQROZXEV-PVLRGYAZSA-N
30384	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 28	MZBFFXLYQTWKNV-INIZCTEOSA-N
30386	114554	9100	-	USP10	UBPO	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 74	MZBFFXLYQTWKNV-INIZCTEOSA-N
30395	121683	57646	-	USP28	-	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 41	MZBFFXLYQTWKNV-INIZCTEOSA-N
30406	120360	55031	-	USP47	TRFP	9606	Homo sapiens	inhibitor	target	Yamanaka S (2020)	31898971	227000	9873	Subquinocin	L-Methionine, N-[[[1,2-dihydro-2-(2-methylpropyl)-1-oxo-4-isoquinolinyl]amino]carbonyl]-, methyl ester|Methyl N-[(2-isobutyl-1-oxo-1,2-dihydro-4-isoquinolinyl)carbamoyl]-L-methioninate	-	CHEMSPIDER	88297784	C20H27N3O4S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Inhibition (%) 33	MZBFFXLYQTWKNV-INIZCTEOSA-N
30530	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Takahashi D (2019)	31606272	239579	10003	Bivalent ligand 263	AUTAC3|Bivalent_ligand_263	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 autophagosome recruiting moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: AUTAC3  (S-guanylation --- BRD4:JQ1)	-
30534	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- ABL1:TAE684)	-
30574	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK2:TAE684)	-
30582	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK7:TAE684)	-
30584	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10010	Bivalent Ligand 264	SK-3-91|Bivalent_Ligand_264	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-91 (CRBN:pomalidomide--- CDK9:TAE684)	-
30718	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- ABL1:TAE684)	-
30740	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK2:TAE684)	-
30748	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK7:TAE684)	-
30750	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide--- CDK9:TAE684)	-
30900	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10011	Bivalent Ligand 267	DB0646|Bivalent_Ligand_267	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0646 (CRBN:Thalidomide--- MAPKAPK2:GNF-7)	-
30950	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK1:TAE)	-
30956	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK2:TAE)	-
30962	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK7:TAE)	-
30964	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CDK9:TAE)	-
30966	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10006	Bivalent Ligand 268	FMF-06-098-1|Bivalent_Ligand_268	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-06-098-1 (VHL:VHL-1--- CHEK1:TAE)	-
31026	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31034	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31038	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK7:Ceritinib)	-
31040	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- CDK9:Ceritinib)	-
31066	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- NUAK1:Ceritinib)	-
31086	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10005	Bivalent Ligand 269	TMX-02-174|Bivalent_Ligand_269	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-174 (CRBN:pomalidomide--- STK38:Ceritinib)	-
31096	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide---ABL1:GNF-7)	-
31136	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10035	Bivalent Ligand 270	DB0662|Bivalent_Ligand_270	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0662 (CRBN:thalidomide--- MAPKAPK2:GNF-7)	-
31178	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK2:Rebastinib)	-
31186	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK7:Rebastinib)	-
31188	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- CDK9:Rebastinib)	-
31214	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10036	Bivalent Ligand 271	TL13-97|Bivalent_Ligand_271	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL13-97 (CRBN:pomalidomide--- STK38:Rebastinib)	-
31226	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide---ABL1:Ponatinib)	-
31284	119490	51347	-	TAOK3	DPK|JIK|MAP3K18	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10033	Bivalent Ligand 272	SB1-G-187|Bivalent_Ligand_272	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-187 (CRBN:Thalidomide--- TAOK3:Ponatinib)	-
31288	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1---ABL1:GNF-7)	-
31328	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10034	Bivalent Ligand 273	DB1114|Bivalent_Ligand_273	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1114 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31350	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1---ABL1:GNF-7)	-
31388	114683	9261	-	MAPKAPK2	MAPKAP-K2|MK-2|MK2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10039	Bivalent Ligand 274	DB1113|Bivalent_Ligand_274	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB1113 (VHL:VHL-1--- MAPKAPK2:GNF-7)	-
31420	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
31428	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
31432	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK7:Ceritinib)	-
31434	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- CDK9:Ceritinib)	-
31452	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- NUAK1:Ceritinib)	-
31466	116457	11329	-	STK38	NDR|NDR1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10040	Bivalent Ligand 275	TMX-02-138|Bivalent_Ligand_275	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-138 (CRBN:pomalidomide--- STK38:Ceritinib)	-
31484	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CDK9:AT7519)	-
31486	107536	1111	-	CHEK1	CHK1	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- CHEK1:AT7519)	-
31504	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10037	Bivalent Ligand 276	MFH-5-126-1|Bivalent_Ligand_276	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-126-1 (CRBN:pomalidomide--- NUAK1:AT7519)	-
31526	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK1:Thienopyrimidines)	-
31530	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10038	Bivalent Ligand 277	RSS0680|Bivalent_Ligand_277	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: RSS0680 (VHL:VHL-1--- CDK2:Thienopyrimidines)	-
31586	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK2:TAE684)	-
31594	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK7:TAE684)	-
31596	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10041	Bivalent Ligand 278	SK-3-93|Bivalent_Ligand_278	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-93 (CRBN:Thalidomide--- CDK9:TAE684)	-
31632	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10042	Bivalent Ligand 279	DB0614|Bivalent_Ligand_279	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DB0614 (CRBN:Thalidomide--- EIF2AK2:Thienopyrimidines)	-
31690	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK2:TAE684)	-
31700	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK9:TAE684)	-
31702	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10067	Bivalent Ligand 283	LT2-49|Bivalent_Ligand_283	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LT2-49 (CRBN:Thalidomide--- CDK7:TAE684)	-
31718	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK1:Dabrafenib)	-
31724	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- CDK2:Dabrafenib)	-
31738	111596	5610	-	EIF2AK2	EIF2AK1|PKR|PPP1R83|PRKR	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10066	Bivalent Ligand 284	DD-03-106|Bivalent_Ligand_284	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: DD-03-106 (CRBN:pomalidomide--- EIF2AK2:Dabrafenib)	-
31756	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10065	Bivalent Ligand 285	SB1-G-192-1|Bivalent_Ligand_285	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-192-1 (CRBN:Thalidomide---ABL1:PP58 (kinobeads) 212391-57-6)	-
31806	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK2:TAE684)	-
31814	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK7:TAE684)	-
31816	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10064	Bivalent Ligand 286	SK-3-89|Bivalent_Ligand_286	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-89 (CRBN:Thalidomide--- CDK9:TAE684)	-
31910	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10061	Bivalent Ligand 289	BSJ-04-178|Bivalent_Ligand_289	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BSJ-04-178 (CRBN:Thalidomide--- CDK9:MRT68921)	-
31934	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK1:Ceritinib)	-
31942	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK2:Ceritinib)	-
31950	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK7:Ceritinib)	-
31952	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10089	Bivalent Ligand 290	TMX-01-160-1|Bivalent_Ligand_290	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-01-160-1 (CRBN:Thalidomide--- CDK9:Ceritinib)	-
31972	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK2:TAE684)	-
31976	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK7:TAE684)	-
31978	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10090	Bivalent Ligand 291	SK-3-87|Bivalent_Ligand_291	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SK-3-87 (CRBN:pomalidomide--- CDK9:TAE684)	-
32012	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10091	Bivalent Ligand 292	MFH-5-115-2|Bivalent_Ligand_292	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-115-2 (CRBN:pomalidomide--- NUAK1:Dinaciclib)	-
32026	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10092	Bivalent Ligand 293	BJG-04-203|Bivalent_Ligand_293	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BJG-04-203 (VHL:pomalidomide--- CDK9:APY-24)	-
32064	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10085	Bivalent Ligand 294	WH-10417-099|Bivalent_Ligand_294	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-10417-099 (CRBN:pomalidomide--- NUAK1:not specified)	-
32134	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK1:Ceritinib)	-
32136	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10088	Bivalent Ligand 297	TMX-02-172|Bivalent_Ligand_297	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TMX-02-172 (CRBN:pomalidomide--- CDK2:Ceritinib)	-
32154	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10083	Bivalent Ligand 298	SB1-G-181|Bivalent_Ligand_298	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-181 (CRBN:pomalidomide---ABL1:TX1-85-1)	-
32202	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10021	Bivalent Ligand 300	SB1-G-200|Bivalent_Ligand_300	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-200 (CRBN:Thalidomide---ABL1:TX1-85-1)	-
32252	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10019	Bivalent Ligand 302	WH-9533-153|Bivalent_Ligand_302	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WH-9533-153 (CRBN:pomalidomide--- NUAK1:not specified)	-
32302	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10018	Bivalent Ligand 305	MFH-5-103-1|Bivalent_Ligand_305	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-103-1 (CRBN:pomalidomide--- CDK7:PND-1186)	-
32340	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10015	Bivalent Ligand 306	SB1-G-194|Bivalent_Ligand_306	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SB1-G-194 (CRBN:Thalidomide--- CDK9:kinobeads)	-
32350	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10016	Bivalent Ligand 307	FMF-04-147-1|Bivalent_Ligand_307	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FMF-04-147-1 (CRBN:pomalidomide--- CDK9:AT7519)	-
32364	115221	9891	-	NUAK1	ARK5	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10013	Bivalent Ligand 308	MFH-5-116-1|Bivalent_Ligand_308	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MFH-5-116-1 (CRBN:pomalidomide--- NUAK1:PND-1186)	-
32540	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Donovan KA (2020)	33275901	231643	10143	Bivalent Ligand 329	ZZ-1-31B|Bivalent_Ligand_329	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: ZZ-1-31B (VHL:VH032---CDK9:SNS032)	-
32566	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu R (2021)	34700270	232271	10111	Bivalent Ligand 337	Bivalent_Ligand_337	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WWL0245 (CRBN:thalidomide---BRD4:WNY0824)	-
32588	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32590	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32592	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Hahn F (2021)	34884662	232751	10103	Bivalent Ligand 345	THAL-SNS032|Bivalent_Ligand_345	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: THAL-SNS032(CRBN:thalidomide---CDK2:SNS032; Coronavirus Project)	-
32622	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Liu H (2021)	34217059	233625	10076	Bivalent Ligand 356	SIAIS056|Bivalent_Ligand_356	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: SIAIS056 (CRBN:pomalidomide---BCR-ABL:dasatinib)	-
32634	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Eron SJ (2021)	34582690	235023	10047	Bivalent Ligand 361	CFT-1297|Bivalent_Ligand_361	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CFT-1297 (CRBN:thalidomide---BRD4:triazoloazepine ligand)	-
32718	107420	983	-	CDK1	CDC2|CDC28A|P34CDC2	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK1:TL13-87)	-
32720	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK2:TL13-87)	-
32728	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK7:TL13-87)	-
32732	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Riching KM (2021)	33190579	235709	8537	Bivalent ligand 120	TL12-186|Bivalent_ligand_120	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TL12-186 (CRBN:pomalidomide --- CDK9:TL13-87)	-
32770	113498	7704	-	ZBTB16	PLZF|ZNF145	9606	Homo sapiens	degradation	target	Shimizu N (2021)	34764413	235318	8560	Bivalent ligand 142	pomalidomide|Bivalent_ligand_142	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: pomalidomide (CRBN:pomalidomide --- ZBTB16:pomalidomide)	-
32772	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Wei J (2021)	34520194	236464	10082	Bivalent ligand 389	MS83|Bivalent_ligand_389	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: MS83 (KEAP1:KEAP1-L --- BRD4:unspecified)	-
32830	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Guo L (2022)	35397401	239587	9988	Bivalent ligand 416	LG-BRD-12|Bivalent_ligand_416	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: LG-BRD-12 (VHL:VHL ligand --- BRD4:JQ1)	-
32846	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Pillow TH (2020)	31674143	239590	10060	Bivalent ligand 420	GNE-987|Bivalent_ligand_420	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: GNE-987 ( VHL:VHL-1 --- BRD4:BET inhibitor)	-
32852	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Gui W (2022)	35802347	238278	10057	Bivalent ligand 423	WJ051|Bivalent_ligand_423	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WJ051  (VHL: VH032 --- BRD4:JQ1)	-
32854	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Gui W (2022)	35802347	238278	10056	Bivalent ligand 424	WJ281|Bivalent_ligand_424	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WJ281  (VHL: VH032 --- BRD4:JQ1)	-
32856	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Gui W (2022)	35802347	238278	10055	Bivalent ligand 425	WJ287|Bivalent_ligand_425	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: WJ287  (VHL: VH032 --- BRD4:JQ1)	-
32873	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Tao Y (2022)	36170674	241674	10370	Bivalent ligand 430	YT117R|Bivalent_ligand_430	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115079	9730	-	VPRBP	DCAF1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: YT117R (DCAF1:MY-1B ---BRD4:JQ1)	-
32875	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Henning NJ (2022)	34994556	235307	10371	Bivalent ligand 431	NJH-1-106|Bivalent_ligand_431	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NJH-1-106 (FEM1B:EN106 ---BRD4:JQ1)	-
32877	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Henning NJ (2022)	34994556	235307	10372	Bivalent ligand 432	NJH-2-142|Bivalent_ligand_432	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115421	10116	-	FEM1B	F1A-ALPHA|F1AA|FEM1-beta	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: NJH-2-142 (FEM1B:EN106 ---ABL1:dasatinib)	-
32890	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- KRAS:iDAB RAS)	-
32892	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- HRAS:iDAB RAS)	-
32894	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10362	Bivalent ligand 438	iDAb RAS-UBOX|Bivalent_ligand_438	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: iDAb RAS-UBOX (CHIP --- NRAS:iDAB RAS)	-
32896	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- KRAS:iDAB RAS)	-
32898	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	109501	3265	-	HRAS	C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- HRAS:iDAB RAS)	-
32900	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Bery N (2020)	32591521	242882	10363	Bivalent ligand 439	UBOX-iDAb RAS|Bivalent_ligand_439	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110952	4893	RP5-1000E10.2	NRAS	ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6	9606	Homo sapiens	target	Standardized BVL Name: UBOX-iDAb RAS (CHIP --- NRAS:iDAB RAS)	-
32910	120581	55294	-	FBXW7	AGO|CDC4|FBW6|FBW7|FBX30|FBXO30|FBXW6|SEL-10|SEL10|hAgo|hCdc4	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10403	Bivalent ligand 443	FBW7-vhhGFP4|Bivalent_ligand_443	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: FBW7-vhhGFP4 (FBW7:vhhGFP4 --- KRAS:GFP)	-
32918	115563	10273	LA16c-313D11.6	STUB1	CHIP|HSPABP2|NY-CO-7|SCAR16|SDCCAG7|UBOX1	9606	Homo sapiens	degradation	recruited e3 ligase	Lim S (2021)	33655066	242886	10399	Bivalent ligand 447	CHIP-vhhGFP4|Bivalent_ligand_447	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	bioPROTAC	Engineered intracellular proteins consisting of a target-binding domain directly fused to an E3 ubiquitin ligase	110043	3845	-	KRAS	C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS|NS3|RASK2	9606	Homo sapiens	target	Standardized BVL Name: CHIP-vhhGFP4 (STUB1:vhhGFP4 --- KRAS:GFP)	-
33012	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10406	Bivalent ligand 469	NJH-2-057|Bivalent_ligand_469	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	107506	1080	tcag7.78	CFTR	ABC35|ABCC7|CF|CFTR/MRP|MRP7|TNR-CFTR|dJ760C5.1	9606	Homo sapiens	target	Standardized BVL Name: NJH-2-057 (OTUB1:EN523 --- deltaF508-CFTR:lumacaftor)	-
33014	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10358	Bivalent ligand 470	LEB-03-144|Bivalent_ligand_470	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: LEB-03-144 (OTUB1:EN523 --- WEE1:AZD1775)	-
33016	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Henning NJ (2022)	35210618	236326	10375	Bivalent ligand 471	LEB-03-146|Bivalent_ligand_471	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113303	7465	-	WEE1	WEE1A|WEE1hu	9606	Homo sapiens	target	Standardized BVL Name: LEB-03-146 (OTUB1:EN523 --- WEE1:AZD1775)	-
33018	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10394	Bivalent ligand 472	FOXO-DUBTAC #6|Bivalent_ligand_472	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	108598	2309	-	FOXO3	AF6q21|FKHRL1|FKHRL1P2|FOXO2|FOXO3A	9606	Homo sapiens	target	Standardized BVL Name: FOXO-DUBTAC #6 (OTUB1:DUBL-X-BCN --- FOXO3A:N3-ODN)	-
33020	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10410	Bivalent ligand 473	p53-DUBTACs #6|Bivalent_ligand_473	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	target	Standardized BVL Name: p53-DUBTACs #6 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33022	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10428	Bivalent ligand 474	p53-DUBTACs #7|Bivalent_ligand_474	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	113010	7157	-	TP53	BCC7|LFS1|P53|TRP53	9606	Homo sapiens	target	Standardized BVL Name: p53-DUBTACs #7 (OTUB1:DUBL-X-BCN --- TP53:p53-ODN)	-
33024	120751	55611	HSPC263	OTUB1	OTB1|OTU1	9606	Homo sapiens	deubiquitination	recruited deubiquitinase	Liu J (2022)	35786952	245265	10417	Bivalent ligand 475	IRF-DUBTAC #7|Bivalent_ligand_475	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	DUBTAC	Deubiquitinase-targeting chimera; structured as DUB binding moiety--linker--target binding moiety; target deubiquitinated via recruited deubiquitinase (DUB)	109869	3661	-	IRF3	-	9606	Homo sapiens	target	Standardized BVL Name: IRF-DUBTAC #7 (OTUB1:DUBL-X-BCN --- IRF3:N3-IRF3-ODN)	-
33029	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Shergalis AG (2023)	36656921	245121	10364	Bivalent ligand 476	1a|Bivalent_ligand_476	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	120224	54876	-	DCAF16	C4orf30	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 1a (DCAF16:1a---BRD4:1a)	-
33069	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation 	target	Mason JW (2023)	37919549	245925	10424	Bivalent ligand 494	CIP-1|Bivalent_ligand_494	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CIP-1 (VHL:MZ1---BRD4:BB3-114)	-
33071	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation 	target	Mason JW (2023)	37919549	245925	10357	Bivalent ligand 495	CIP-3|Bivalent_ligand_495	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CIP-3 (VHL:MZ1---BRD4:BB2-109)	-
33073	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation 	target	Mason JW (2023)	37919549	245925	10422	Bivalent ligand 496	CIP-4|Bivalent_ligand_496	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CIP-4 (VHL:MZ1---BRD4:BB2-109)	-
33150	113258	7415	-	VCP	ALS14|HEL-220|HEL-S-70|IBMPFD|IBMPFD1|TERA|p97	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2020)	32408336	223364	8581	NMS-873	Pyridine, 3-[3-(cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-|NMS-873|MFCD28009371|3-[3-Cyclopentylsulfanyl-5-(4'-methanesulfonyl-2-methylbiphenyl-4-yloxymethyl)-[1,2,4]triazol-4-yl]-pyridine|3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]-pyridine|3-[3-(Cyclopentylsulfanyl)-5-({[2-methyl-4'-(methylsulfonyl)-4-biphenylyl]oxy}methyl)-4H-1,2,4-triazol-4-yl]pyridine	-	CHEMSPIDER	29398603	C27H28N4O3S2	small molecule	-	1418013-75-8	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: p97 inhibitor; viral inhibition mechanism undetermined	UJGTUKMAJVCBIS-UHFFFAOYSA-N
33188	107027	545	-	ATR	FCTCS|FRP1|MEC1|SCKL|SCKL1	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Garcia G (2021)	33784499	240019	10213	berzosertib	VE-822|UNII:L423PRV3V3|VX-970|Berzosertib|L423PRV3V3|5-[4-(Isopropylsulfonyl)phenyl]-3-(3-{4-[(methylamino)methyl]phenyl}-1,2-oxazol-5-yl)-2-pyrazinamine|2-Pyrazinamine, 3-[3-[4-[(methylamino)methyl]phenyl]-5-isoxazolyl]-5-[4-[(1-methylethyl)sulfonyl]phenyl]-	-	CHEMSPIDER	30773968	C24H25N5O3S	small molecule	-	1232416-25-9	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: ATR inhibitor (PMID: 31018854); viral inhibition mechanism undetermined	JZCWLJDSIRUGIN-UHFFFAOYSA-N
33305	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor/sars-cov-2 activator	target	Chen IP (2022)	35839775	232204	10195	dBET6	-	-	CHEMSPIDER	71046111	C42H45ClN8O7S	small molecule	-	-	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:BRD4 inhibitor; BRD3 inhibition results in enhanced viral replication in cultured cells and in mice	JGQPZPLJOBHHBK-UFXYQILXSA-N
33307	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	inhibitor/sars-cov-2 activator	target	Chen IP (2022)	35839775	232204	10243	JQ1	JQ1|(6s)-6-(2-Tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepin-10-ium|(+)-JQ1|(S)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate|6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6S)-|JQ-1|2-Methyl-2-propanyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate|MFCD22683748|1MRH0IMX0W|JQ 1(+)	-	CHEMSPIDER	26323622	C23H25ClN4O2S	small molecule	-	1268524-70-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction:BRD4 inhibitor; BRD3 inhibition results in enhanced viral replication in cultured cells and in mice	DNVXATUJJDPFDM-KRWDZBQOSA-N
33355	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2023)	36644320	239397	10278	THAL-SNS-032	N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)-1-{[(2-{2-[2-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)ethoxy]ethoxy}ethyl)carbamoyl]methyl}piperidine-4-carboxamide	-	CHEMSPIDER	65324400	C40H52N8O10S2	small molecule	-	2139287-33-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: CDK9 inhibitor; viral inhibition mechanism undetermined; anti-delta and omicron activity determined by a Caco-2-F03 cell line platform and caspase 3/7 activity as readout method	BXDZOYLPNAIDOC-UHFFFAOYSA-N
33356	107457	1022	-	CDK7	CAK1|CDKN7|HCAK|MO15|STK1|p39MO15	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bojkova D (2023)	36644320	239397	10225	LDC4297	LDC-4297|Pyrazolo[1,5-a]-1,3,5-triazin-4-amine, 8-(1-methylethyl)-2-(3-piperidinyloxy)-N-[[2-(1H-pyrazol-1-yl)phenyl]methyl]-|8-Isopropyl-2-(3-piperidinyloxy)-N-[2-(1H-pyrazol-1-yl)benzyl]pyrazolo[1,5-a][1,3,5]triazin-4-amine	-	CHEMSPIDER	58790025	C23H28N8O	small molecule	-	1453834-21-3	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: CDK7 inhibitor; viral inhibition mechanism undetermined; anti-delta and omicron activity determined by a Caco-2-F03 cell line platform and caspase 3/7 activity as readout method	LSGRZENCFIIHNV-UHFFFAOYSA-N
33457	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10176	dinaciclib	Dinaciclib|SCH 727965|SCH727965|2-[(2S)-1-(3-Ethyl-7-{[(1-oxido-3-pyridinyl)methyl]amino}pyrazolo[1,5-a]pyrimidin-5-yl)-2-piperidinyl]ethanol|4V8ECV0NBQ|2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-	-	CHEMSPIDER	25027387	C21H28N6O2	small molecule	-	779353-01-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human CDK2/5/9 inhibitor;  antiviral activity against SARS-CoV-2 in VERO-E6 and ACE2-A549 cells	PIMQWRZWLQKKBJ-SFHVURJKSA-N
33459	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	inhibitor/sars-cov-2 inhibitor	target	Bouhaddou M (2020)	32645325	223689	10176	dinaciclib	Dinaciclib|SCH 727965|SCH727965|2-[(2S)-1-(3-Ethyl-7-{[(1-oxido-3-pyridinyl)methyl]amino}pyrazolo[1,5-a]pyrimidin-5-yl)-2-piperidinyl]ethanol|4V8ECV0NBQ|2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-	-	CHEMSPIDER	25027387	C21H28N6O2	small molecule	-	779353-01-4	BIOGRID	-	-	-	-	-	-	-	-	-	-	Coronavirus Project SARS-CoV-2 indirect chemical interaction: human CDK2/5/9 inhibitor;  antiviral activity against SARS-CoV-2 in VERO-E6 and ACE2-A549 cells	PIMQWRZWLQKKBJ-SFHVURJKSA-N
33510	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Xie H (2023)	36749666	248602	10743	Bivalent ligand 513	Degrader 13|bivalent_ligand_513	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Degrader 13 (CRBN: 1,2,3-trisubstituted PDHU --- BRD4:JQ1)	-
33560	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Bai L (2017)	28209615	256615	10755	Bivalent ligand 526	BETd-246|bivalent_ligand_526	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BETd-246 (CRBN:thalidomide --- BRD4:BETi-211)	-
33566	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu J (2023)	37289649	256617	10758	Bivalent ligand 529	BD-7148|bivalent_ligand_529	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BD-7148 (CRBN:pomalidomide --- BRD4:QCA276)	-
33568	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Hu J (2023)	37289649	256617	10759	Bivalent ligand 530	BD-9136|bivalent_ligand_530	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: BD-9136 (CRBN:pomalidomide --- BRD4:QCA276)	-
33606	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Ding M (2023)	36563515	256624	10772	Bivalent ligand 543	degrader 8b|bivalent_ligand_543	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: degrader 8b (CRBN:lenalidomide --- BRD4:JQ1)	-
33644	106543	25	RP11-83J21.1	ABL1	ABL|JTK7|bcr/abl|c-ABL|c-ABL1|p150|v-abl	9606	Homo sapiens	degradation	target	Jiang L (2021)	34094836	254471	10790	Bivalent ligand 561	Compound 7o|bivalent_ligand_561	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 7o (CRBN:pomalidomide --- Bcr-Abl:GZD824)	-
33670	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	degradation	target	Murgai A (2022)	35852517	256632	10803	Bivalent ligand 574	PROTAC 17|bivalent_ligand_574	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC 17 (CRBN:thalidomide --- USP7:XL188)	-
33680	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	degradation	target	Pei Y (2022)	35691827	256637	10808	Bivalent ligand 579	U7D-1|bivalent_ligand_579	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: U7D-1 (CRBN:pomalidomide --- USP7: compound 4)	-
33734	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Basu AA (2024)	38965383	254538	10825	Bivalent ligand 604	22-JQ1|bivalent_ligand_604	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	117649	26263	-	FBXO22	FBX22|FISTC1	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 22-JQ1 (FBXO22:22 --- BRD4:JQ1)	-
33742	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Fan H (2023)	37683536	254595	10829	Bivalent ligand 608	precursor 1a|bivalent_ligand_608	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	nano-PROTAC	A nano-particle containing a Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety, which is activatable in the presence of a specific stimulus; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: precursor 1a (VHL:VHL Ligand with GSH-responsive capping group --- BRD4:JQ1)	-
33744	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Wu T (2023)	37672930	254597	10830	Bivalent ligand 609	CP-07|bivalent_ligand_609	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CP-07 (CRBN:thalidomide --- CDK9:LWT-111)	-
33778	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Kumarasamy V (2023)	37626264	254608	10846	Bivalent ligand 625	FN-POM|bivalent_ligand_625	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: FN-POM (CRBN:pomalidomide --- CDK2:N-1501)	-
33798	115114	9768	L5	KIAA0101	NS5ATP9|OEATC|OEATC-1|OEATC1|PAF|PAF15|p15(PAF)|p15/PAF|p15PAF	9606	Homo sapiens	degradation	target	Li Y (2023)	37552639	254640	10855	Bivalent ligand 634	AD4|bivalent_ligand_634	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: AD4 (CRBN:pomalidomide --- PCLAF:SM1044)	-
33832	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Ayinde OR (2023)	37465296	254805	10867	Bivalent ligand 646	Compound 14|bivalent_ligand_646	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 14 (CRBN:thalidomide --- CDK9:AT7519)	-
33854	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Bagka M (2023)	37393376	254824	10875	Bivalent ligand 654	HPP-9|bivalent_ligand_654	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: HPP-9 (CRBN:Hydroxythalidomide --- BRD4:HPI-1)	-
33874	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10885	Bivalent ligand 664	14|bivalent_ligand_664	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 14 (CRBN:pomalidomide --- BRD4:JQ1)	-
33876	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10886	Bivalent ligand 665	15|bivalent_ligand_665	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 15 (CRBN:pomalidomide --- BRD4:JQ1)	-
33878	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kargbo RB (2019)	31620218	256641	10887	Bivalent ligand 666	16|bivalent_ligand_666	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 16 (CRBN:pomalidomide --- BRD4:JQ1)	-
33926	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Wang L (2021)	33664520	256648	10909	Bivalent ligand 688	CPS2|bivalent_ligand_688	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: CPS2 (CRBN:pomalidomide --- CDK2:J2)	-
33938	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chen J (2022)	35395439	256652	10915	Bivalent ligand 694	7f|bivalent_ligand_694	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 7f (CRBN:pomalidomide --- BRD4:ABBV-744)	-
33940	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Chen J (2022)	35395439	256652	10916	Bivalent ligand 695	13d|bivalent_ligand_695	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: 13d (CRBN:pomalidomide ---BRD4:ABBV-744)	-
33979	108009	1642	-	DDB1	DDBA|UV-DDB1|XAP1|XPCE|XPE|XPE-BF	9606	Homo sapiens	degradation	recruited e3 ligase	Dieter SM (2021)	34289372	255474	10935	Bivalent ligand 714	NCT02|bivalent_ligand_714	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Molecular Glue	Single chemical moiety that contacts both the E3 and the target in a ternary complex; structured as a single chemical entity without linkers; target degraded via UPS or otherwise inactivated in the ternary complex	114339	8812	-	CCNK	CPR4	9606	Homo sapiens	target	Standardized BVL Name: NCT02 (DDB1:NCT02 --- CCNK:NCT02)	-
33982	107452	1017	-	CDK2	CDKN2|p33(CDK2)	9606	Homo sapiens	degradation	target	Hati S (2021)	34560429	255476	10936	Bivalent ligand 715	PROTAC-8|bivalent_ligand_715	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PROTAC-8 (VHL:VH032 --- CDK2:AZD5438)	-
34006	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Pei J (2021)	34816823	256657	10945	Bivalent ligand 724	10f|bivalent_ligand_724	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	AUTAC/ATTEC	Autophagosome Tethering Compound; structured as a LC3 binding moiety--linker--target binding moiety; target degraded via autophagic degradation	123565	81631	-	MAP1LC3B	ATG8F|LC3B|MAP1A/1BLC3|MAP1LC3B-a	9606	Homo sapiens	autophagy-targeting protein	Standardized BVL Name: 10f (MAP1LC3B:GW5074 --- BRD4:JQ1)	-
34044	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2021)	34432252	256663	10957	Bivalent ligand 736	PHOTAC-I-3|bivalent_ligand_736	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-3 (CRBN:lenalidomide --- BRD4:JQ1)	-
34048	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Reynders M (2021)	34432252	256663	10958	Bivalent ligand 737	PHOTAC-I-10|bivalent_ligand_737	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	Opto-PROTAC	PROTAC variant in which a light-inducible degradation tag can be used to regulate target degradation activity; structured as E3 binding moiety with a photolabile caging group--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PHOTAC-I-10 (CRBN:thalidomide --- BRD4:JQ1)	-
34072	111863	5928	-	RBBP4	NURF55|RBAP48|lin-53	9606	Homo sapiens	degradation	target	Liu Z (2021)	33606537	256665	10964	Bivalent ligand 743	E7|bivalent_ligand_743	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: E7 (CRBN:4-hydroxythalidomide --- RBBP4:EPZ6438)	-
34074	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Dragovich PS (2021)	33596073	256666	10965	Bivalent ligand 744	compound 8|bivalent_ligand_744	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 8 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34076	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Dragovich PS (2021)	33596073	256666	10966	Bivalent ligand 745	compound 9|bivalent_ligand_745	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 9 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34078	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Dragovich PS (2021)	33596073	256666	10967	Bivalent ligand 746	compound 12|bivalent_ligand_746	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 12 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34080	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Dragovich PS (2021)	33596073	256666	10968	Bivalent ligand 747	compound 13|bivalent_ligand_747	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	113269	7428	-	VHL	HRCA1|RCA1|VHL1|pVHL	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: compound 13 (VHL:VH032 --- BRD4:compound 4-fragment 5)	-
34114	117036	23476	-	BRD4	CAP|HUNK1|HUNKI|MCAP	9606	Homo sapiens	degradation	target	Kim SA (2019)	30684871	220042	10977	Bivalent ligand 756	TD-428|bivalent_ligand_756	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: TD-428 (CRBN:TD-106 --- BRD4:JQ1)	-
34128	113622	7874	-	USP7	HAUSP|TEF1	9606	Homo sapiens	degradation	target	Yi J (2023)	37291217	253028	10980	Bivalent ligand 759	PU7-1|bivalent_ligand_759	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: PU7-1 (CRBN:lenalidomaide --- USP7:XL-177A)	-
34200	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Tokarski RJ (2023)	37071962	256455	11008	Bivalent ligand 787	Compound 15e|bivalent_ligand_787	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 15e (CRBN:thalidomide --- CDK9:AT7519)	-
34202	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Tokarski RJ (2023)	37071962	256455	11009	Bivalent ligand 788	Compound 16|bivalent_ligand_788	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	119360	51185	AD-006	CRBN	MRT2|MRT2A	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Compound 16 (CRBN:thalidomide --- CDK9:AT7519)	-
34264	107459	1025	RP11-228B15.5	CDK9	C-2k|CDC2L4|CTK1|PITALRE|TAK	9606	Homo sapiens	degradation	target	Pei J (2023)	36750097	256521	11033	Bivalent ligand 811	Conjugate 955|bivalent_ligand_811	-	BIOGRID	-	-	small molecule	-	-	BIOGRID	PROTAC	Proteolysis Targeting Chimera; structured as E3 binding moiety--linker--target binding moiety; target degraded via UPS	115156	9817	-	KEAP1	INrf2|KLHL19	9606	Homo sapiens	recruited e3 ligase	Standardized BVL Name: Conjugate 955 (KEAP1:piperlongumine (PL) --- CDK9:SNS-032)	-
