Welcome to the BioGRID Download File Repository


Please use the file navigator below to browse and download archived BioGRID project files. All data provided are 100% freely available to both academic and commercial users under the MIT License, and are provided WITHOUT ANY WARRANTY. If you have any questions, please feel free to contact us. Publications are requested to please cite the original contributing authors (where applicable) and also:
Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M. Biogrid: A General Repository for Interaction Datasets. Nucleic Acids Res. Jan 1, 2006; 34:D535-9.


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149.11 MB
BIOGRID-ALL-4.4.214.mitab.zip

BIOGRID-ALL-4.4.214.mitab.zip

This zip archive contains a single file formatted in PSI MITAB level 2.5 compatible Tab Delimited Text file format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems. For more information on this format, check out our wiki.
48.95 MB
BIOGRID-ALL-4.4.214.psi.zip

BIOGRID-ALL-4.4.214.psi.zip

This zip archive contains a single file formatted in PSI level 1.0 compatible XML format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems.

WARNING: This file format is obsolete, we highly recommend you use the PSI 2.5 format instead.
160.44 MB
BIOGRID-ALL-4.4.214.psi25.zip

BIOGRID-ALL-4.4.214.psi25.zip

This zip archive contains a single file formatted in PSI XML level 2.5 compatible XML format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems. For more information on this format, check out our wiki.
55.63 MB
BIOGRID-ALL-4.4.214.tab.zip

BIOGRID-ALL-4.4.214.tab.zip

This zip archive contains a single file formatted in Microsoft Excel tab delimited text file format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
101.86 MB
BIOGRID-ALL-4.4.214.tab2.zip

BIOGRID-ALL-4.4.214.tab2.zip

This zip archive contains a single file formatted in BioGRID Tab 2.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
147.52 MB
BIOGRID-ALL-4.4.214.tab3.zip

BIOGRID-ALL-4.4.214.tab3.zip

This zip archive contains a single file formatted in BioGRID Tab 3.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID for all species and experimental systems. For more information on this format, check out our wiki.
1.17 MB
BIOGRID-CHEMICALS-4.4.214.chemtab.zip

BIOGRID-CHEMICALS-4.4.214.chemtab.zip

This zip file contains a listing of protein-chemical interactions for the entire BioGRID dataset. The file is a modified version of the BioGRID Tab 2.0 format, designed to add in columns for chemical specific annotation. You can get full information on the formatting of this file in our wiki.
2.00 MB
BIOGRID-CORONAVIRUS-4.4.214.tab3.zip
259.06 MB
BIOGRID-IDENTIFIERS-4.4.214.tab.zip

BIOGRID-IDENTIFIERS-4.4.214.tab.zip

This zip archive contains a single file formatted in Microsoft Excel tab delimited text file format containing a list of mappings between different identifiers stored in our database and the identifiers used in our downloads. You can use this file to map from one identifier type to another. For more information on this format, check out our wiki.
27.00 MB
BIOGRID-MV-Physical-4.4.214.mitab.zip

BIOGRID-MV-Physical-4.4.214.mitab.zip

This zip file contains a listing of Physical multi-validated interactions for the entire BioGRID dataset. For details on how this file is generated, visit our multi-validated details wiki page. The file is provided in PSI MITAB level 2.5 compatible Tab Delimited Text file format. You can get full information on the formatting of this file in our wiki.
32.07 MB
BIOGRID-MV-Physical-4.4.214.psi25.zip

BIOGRID-MV-Physical-4.4.214.psi25.zip

This zip file contains a listing of Physical multi-validated interactions for the entire BioGRID dataset. For details on how this file is generated, visit our multi-validated details wiki page. The file is provided in PSI XML level 2.5 compatible XML format. You can get full information on the formatting of this file in our wiki.
16.34 MB
BIOGRID-MV-Physical-4.4.214.tab2.zip

BIOGRID-MV-Physical-4.4.214.tab2.zip

This zip file contains a listing of Physical multi-validated interactions for the entire BioGRID dataset. For details on how this file is generated, visit our multi-validated details wiki page. The file is provided in BioGRID Tab 2.0 format.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
25.09 MB
BIOGRID-MV-Physical-4.4.214.tab3.zip

BIOGRID-MV-Physical-4.4.214.tab3.zip

This zip file contains a listing of Physical multi-validated interactions for the entire BioGRID dataset. For details on how this file is generated, visit our multi-validated details wiki page. The file is provided in BioGRID Tab 3.0 format. You can get full information on the formatting of this file in our wiki.
152.99 MB
BIOGRID-ORGANISM-4.4.214.mitab.zip

BIOGRID-ORGANISM-4.4.214.mitab.zip

This zip archive contains multiple files formatted in PSI MITAB level 2.5 compatible Tab Delimited Text format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism. For more information on this format, check out our wiki.
53.95 MB
BIOGRID-ORGANISM-4.4.214.psi.zip

BIOGRID-ORGANISM-4.4.214.psi.zip

This zip archive contains multiple files formatted in PSI Level 1.0 compatible XML format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism.

WARNING: This file format is obsolete, we highly recommend you use the PSI 2.5 format instead.
164.52 MB
BIOGRID-ORGANISM-4.4.214.psi25.zip

BIOGRID-ORGANISM-4.4.214.psi25.zip

This zip archive contains multiple files formatted in PSI Level 2.5 compatible XML format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism. For more information on this format, check out our wiki.
56.89 MB
BIOGRID-ORGANISM-4.4.214.tab.zip

BIOGRID-ORGANISM-4.4.214.tab.zip

This zip archive contains multiple files formatted in Microsoft Excel Tab Delimited Text format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
104.02 MB
BIOGRID-ORGANISM-4.4.214.tab2.zip

BIOGRID-ORGANISM-4.4.214.tab2.zip

This zip archive contains multiple files formatted in BioGRID Tab 2.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
150.98 MB
BIOGRID-ORGANISM-4.4.214.tab3.zip

BIOGRID-ORGANISM-4.4.214.tab3.zip

This zip archive contains multiple files formatted in BioGRID Tab 3.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Organism. For more information on this format, check out our wiki.
31.91 MB
BIOGRID-OSPREY_DATASETS-4.4.214.osprey.zip

BIOGRID-OSPREY_DATASETS-4.4.214.osprey.zip

This zip archive contains multiple files formatted in Osprey Network Visualization System Custom Network format containing all interaction and associated annotation data from the BIOGRID separated into seperate Organisms and Experimental Systems to be used in Osprey. For more information on this format, check out our wiki.
3.51 MB
BIOGRID-PROJECT-autophagy_project-4.4.214.zip

BIOGRID-PROJECT-autophagy_project-4.4.214.zip

This zip file contains multiple files comprising Interactions, Post-Translational Modifications, and Chemical-Interactions for the Autophagy Project. For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
1.71 MB
BIOGRID-PROJECT-covid19_coronavirus_project-4.4.214.zip

BIOGRID-PROJECT-covid19_coronavirus_project-4.4.214.zip

This zip file contains multiple files comprising Interactions and Post-Translational Modifications for the COVID-19 Coronavirus Project. For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
1.81 MB
BIOGRID-PROJECT-fanconi_anemia_project-4.4.214.zip

BIOGRID-PROJECT-fanconi_anemia_project-4.4.214.zip

This zip file contains multiple files comprising Interactions, Post-Translational Modifications, and Chemical-Interactions for the Fanconi Anemia Project. For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
4.02 MB
BIOGRID-PROJECT-glioblastoma_project-4.4.214.zip

BIOGRID-PROJECT-glioblastoma_project-4.4.214.zip

This zip file contains multiple files comprising Interactions, Post-Translational Modifications, and Chemical-Interactions for the Glioblastoma Project. For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
6.53 MB
BIOGRID-PROJECT-kinome_project_sc-4.4.214.zip

BIOGRID-PROJECT-kinome_project_sc-4.4.214.zip

This zip file contains multiple files comprising Interactions, Post-Translational Modifications, and Chemical-Interactions for the BioGRID Kinome Project (Sc). For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
28.63 MB
BIOGRID-PROJECT-ups_project-4.4.214.zip

BIOGRID-PROJECT-ups_project-4.4.214.zip

This zip file contains multiple files comprising Interactions, Post-Translational Modifications, and Chemical-Interactions for the Ubiquitin-Proteasome System Project. For details on how these files are generated, visit our download format details wiki page. The files are provided in Tab-Delimited format. You can get full information on the formatting of this file in our wiki.
56.47 MB
BIOGRID-PTMS-4.4.214.ptm.zip

BIOGRID-PTMS-4.4.214.ptm.zip

This zip archive contains multiple files formatted in PTM and PTMREL format containing post translational modification data and associated annotation data from the BIOGRID. For more information on this format, check out our wiki.
153.00 MB
BIOGRID-SYSTEM-4.4.214.mitab.zip

BIOGRID-SYSTEM-4.4.214.mitab.zip

This zip archive contains multiple files formatted in PSI MITAB level 2.5 compatible Tab Delimited Text format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System. For more information on this format, check out our wiki.
70.15 MB
BIOGRID-SYSTEM-4.4.214.psi.zip

BIOGRID-SYSTEM-4.4.214.psi.zip

This zip archive contains multiple files formatted in PSI LEvel 1.0 compatible XML format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System.

WARNING: This file format is obsolete, we highly recommend you use the PSI 2.5 format instead.
175.49 MB
BIOGRID-SYSTEM-4.4.214.psi25.zip

BIOGRID-SYSTEM-4.4.214.psi25.zip

This zip archive contains multiple files formatted in PSI Level 2.5 compatible XML format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System. For more information on this format, check out our wiki.
57.42 MB
BIOGRID-SYSTEM-4.4.214.tab.zip

BIOGRID-SYSTEM-4.4.214.tab.zip

This zip archive contains multiple files formatted in Microsoft Excel Tab Delimited Text format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
104.20 MB
BIOGRID-SYSTEM-4.4.214.tab2.zip

BIOGRID-SYSTEM-4.4.214.tab2.zip

This zip archive contains multiple files formatted in BioGRID Tab 2.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System.

WARNING: This file format is obsolete, we highly recommend you use the BioGRID Tab 3 format instead.
151.32 MB
BIOGRID-SYSTEM-4.4.214.tab3.zip

BIOGRID-SYSTEM-4.4.214.tab3.zip

This zip archive contains multiple files formatted in BioGRID Tab 3.0 Delimited Text file format containing all interaction and associated annotation data from the BIOGRID separated into seperate distinct files based on Experimental System. For more information on this format, check out our wiki.

BioGRID Release 4.4.214

This download directory contains the 4.4.214 interaction data release from the BioGRID. This release was compiled on September. 25th, 2022 and contains all curated interaction data processed prior to this date. If you are starting a new project using our data, it is HIGHLY recommended that you use the data files in the most recent release as it will contain the most up-to-date version of our interaction dataset. The best dataset to use is in the CURRENT RELEASE directory.


For more information about each of the available files, simply mouse over to see a description.


To download each file, simply left click on it to start the download process.